Hs01940892_s1

• Gene Symbol: PRNP
• Gene Name: prion protein
• Gene Aliases: ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30
• Chromosome Location: Chr.20: 4686151 - 4701588 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PRNP
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000311.3	NP_000302.1	2	2124		130
	NM_001080121.1	NP_001073590.1	2	2119		130
	NM_001080122.1	NP_001073591.1	2	2115		130
	NM_001080123.1	NP_001073592.1	2	1988		130
	NM_001271561.1	NP_001258490.1	2	2124		130
	NM_183079.2	NP_898902.1	2	2120		130
GenBank mRNA	AK090575.1	-	3	1723		130
	AY008282.1	-	2	1795		130
	BC012844.1	-	2	1799	3863784	130
	BC016809.1	-	1	952		130
	BC022532.1	-	2	1812	4813982	130
	D00015.1	-	1	1804		130
	M13667.1	-	1	1804		130
	M13899.1	-	2	1801		130

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC2000006576.hg.1
This assay targets the same location as HTA transcript cluster(s) TC20000051.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Inventoried, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PRNP

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
cellular copper ion homeostasis
response to oxidative stress
cell cycle arrest
learning or memory
metabolic process
negative regulation of interferon-gamma production
negative regulation of interleukin-17 production
negative regulation of interleukin-2 production
regulation of protein localization
cellular response to drug
negative regulation of apoptotic process
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of activated T cell proliferation
response to cadmium ion
negative regulation of T cell receptor signaling pathway
protein homooligomerization
negative regulation of calcineurin-NFAT signaling cascade
cellular response to copper ion
regulation of potassium ion transmembrane transport

Function(s)

copper ion binding
protein binding
lamin binding
microtubule binding
tubulin binding
identical protein binding
ATP-dependent protein binding
ion channel binding
chaperone binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR20000830.hg.1	ENST00000379440.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000830.hg.1	ENST00000430350.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000830.hg.1	ENST00000444805.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000830.hg.1	NM_000311.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000830.hg.1	NM_001080121.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000830.hg.1	NM_001080122.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000830.hg.1	NM_001080123.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000830.hg.1	NM_183079.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000830.hg.1	TC20000051.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR20000831.hg.1	ENST00000379440.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000831.hg.1	ENST00000430350.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000831.hg.1	NM_000311.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000831.hg.1	NM_001080121.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000831.hg.1	NM_001080122.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000831.hg.1	NM_001080123.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000831.hg.1	NM_183079.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000831.hg.1	TC20000051.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR20000817.hg.1	NM_001080123.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000817.hg.1	TC20000051.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR20000829.hg.1	ENST00000379440.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000829.hg.1	ENST00000430350.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000829.hg.1	ENST00000444805.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000829.hg.1	NM_000311.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000829.hg.1	NM_001080121.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000829.hg.1	NM_001080122.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000829.hg.1	NM_001080123.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000829.hg.1	NM_183079.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000829.hg.1	TC20000051.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR2000145267.hg.1	NM_001080123.2	Refseq
Affymetrix Human Clariom D Assay	PSR2000145267.hg.1	TC2000006576.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR2000145267.hg.1	NM_001080123.2	Refseq
Affymetrix Human Clariom D Assay	PSR2000145268.hg.1	ENST00000457586.1	Ensembl
Affymetrix Human Clariom D Assay	PSR2000145268.hg.1	NM_001080123.2	Refseq
Affymetrix Human Clariom D Assay	PSR2000145268.hg.1	TC2000006576.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR2000145268.hg.1	ENST00000457586.1	Ensembl
Affymetrix Human Clariom D Assay	PSR2000145268.hg.1	NM_001080123.2	Refseq