Hs03666981_s1

• Gene Symbol: GHR
• Gene Name: growth hormone receptor
• Gene Aliases: GHBP, GHIP
• Chromosome Location: Chr.5: 42423775 - 42721878 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: GHR
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001242406.2	NP_001229335.1	1	142		92
GenBank mRNA	Z11850.1	-	1	144		92

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	uncharacterized LOC101926960	LOC101926960		-390.1kb	Anti-sense	Chr. 5 - 42155833 - 42175345 on NCBI Build GRCh38
Downstream	coiled-coil domain containing 152	CCDC152	CH5400	190.9kb	Sense	Chr. 5 - 42756818 - 42802437 on NCBI Build GRCh38

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0500007258.hg.1
This assay targets the same location as HTA transcript cluster(s) TC05000191.hg.1

Additional Information:

This assay is in the 5'UTR region of the NM_001242406.2,Z11850.1 transcripts.

• Set Membership: Amplicon length between 86 and 100, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

activation of MAPK activity
allantoin metabolic process
citrate metabolic process
2-oxoglutarate metabolic process
succinate metabolic process
oxaloacetate metabolic process
isoleucine metabolic process
valine metabolic process
creatine metabolic process
fatty acid metabolic process
endocytosis
JAK-STAT cascade
cytokine-mediated signaling pathway
taurine metabolic process
cellular response to hormone stimulus
regulation of multicellular organism growth
positive regulation of multicellular organism growth
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
activation of JAK2 kinase activity
multicellular organism metabolic process
creatinine metabolic process
insulin-like growth factor receptor signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation
growth hormone receptor signaling pathway
JAK-STAT cascade involved in growth hormone signaling pathway

Function(s)

cytokine receptor activity
protein binding
peptide hormone binding
protein kinase binding
protein homodimerization activity
proline-rich region binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR05002261.hg.1	TC05000191.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05002261.hg.1	NM_001242406.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149074.hg.1	NM_001242406.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149074.hg.1	NM_001242406.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149074.hg.1	TC0500007258.hg.1	Clariom D TC