Hs04232343_m1

• Gene Symbol: MAVS
• Gene Name: mitochondrial antiviral signaling protein
• Gene Aliases: CARDIF, IPS-1, IPS1, VISA
• Chromosome Location: Chr.20: 3846799 - 3876123 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MAVS
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NR_037921.1		3 - 4	463		61
GenBank mRNA	AK296897.1	-	3 - 4	428		61
	EF467324.1	-	2 - 3	291		61

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	DC347239.1	-	3 - 4	428		Chr. 20 - 3846834 - 3862362 [+] on Build GRCh38	61
GenBankmRNA	DC375415.1	-	3 - 4	425		Chr. 20 - 3846837 - 3862409 [+] on Build GRCh38	61
GenBankmRNA	DC390311.1	-	3 - 4	425		Chr. 20 - 3846837 - 3862393 [+] on Build GRCh38	61
GenBankmRNA	DC407571.1	-	3 - 4	425		Chr. 20 - 3846837 - 3862391 [+] on Build GRCh38	61

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	adaptor related protein complex 5 sigma 1 subunit	AP5S1	C20orf29	-32.3kb	Sense	Chr. 20 - 3820524 - 3825307 on NCBI Build GRCh38
Downstream	pantothenate kinase 2	PANK2	C20orf48, HARP, HSS, NBIA1, PKAN	26.4kb	Sense	Chr. 20 - 3888839 - 3929882 on NCBI Build GRCh38

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC2000006561.hg.1
This assay targets the same location as HTA transcript cluster(s) TC20000043.hg.1

• Set Membership: Amplicon length less than or equal to 70, Homo sapiens, Probe spans exons

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
activation of innate immune response
positive regulation of defense response to virus by host
signal transduction
negative regulation of type I interferon production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of protein import into nucleus, translocation
RIG-I signaling pathway
defense response to bacterium
positive regulation of transcription factor import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of viral genome replication
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity
defense response to virus
positive regulation of type I interferon-mediated signaling pathway
cellular response to exogenous dsRNA
positive regulation of chemokine (C-C motif) ligand 5 production
positive regulation of IP-10 production
regulation of peroxisome organization

Function(s)

signal transducer activity
protein binding
protein kinase binding
CARD domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR20000737.hg.1	ENST00000358134.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000737.hg.1	ENST00000416600.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000737.hg.1	ENST00000428216.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20000737.hg.1	NM_001206491.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000737.hg.1	NM_020746.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000737.hg.1	NR_037921.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20000737.hg.1	TC20000043.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	ENST00000416600.6	Ensembl
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	ENST00000428216.3	Ensembl
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	NM_001206491.1	Refseq
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	NM_020746.4	Refseq
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	NR_037921.1	Refseq
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	TC2000006561.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	ENST00000416600.6	Ensembl
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	ENST00000428216.3	Ensembl
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	NM_001206491.1	Refseq
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	NM_020746.4	Refseq
Affymetrix Human Clariom D Assay	PSR2000145158.hg.1	NR_037921.1	Refseq