Hs04274649_s1

Gene Symbol:

MIR4686 TH

Gene Name:

microRNA 4686

tyrosine hydroxylase

Gene Aliases:

-

DYT14, DYT5b, TYH

Chromosome Location:

Chr.11: 2173063 - 2173138 on Build GRCh38

Chromosome Location:

Chr.11: 2163929 - 2174081 on Build GRCh38

Species:

Human

Species Specific ID (Flybase ID):

-

-

Assay Details

Gene Symbol: MIR4686
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NR_039834.1		1	36		55

Gene Symbol: TH
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_011520335.2	XP_011518637.1	1			55

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Downstream	achaete-scute family bHLH transcription factor 2	ASCL2	ASH2, HASH2, MASH2, bHLHa45	95.4kb	Anti-sense	Chr. 11 - 2268498 - 2270952 on NCBI Build GRCh38

More Information

Updated Mapping Information

This assay is designed to target a precursor miRNA (pre-miRNA) target. It may not discriminate between the primary transcript (pri-miRNA) and the pre-miRNA for this miRNA. If you are looking for an assay to detect the mature miRNA, please search the MicroRNA collection of assays.
This assay targets the same location as Clariom D transcript cluster(s) TC1100006563.hg.1
This assay targets the same location as HTA transcript cluster(s) TC11000059.hg.1

Additional Information:

This assay is in the 5'UTR region of the XM_011520335.2 transcripts.

• Set Membership: Amplicon length less than or equal to 70, 3' Most, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Gene Ontology Categories:

Process(es)

response to hypoxia
synaptic transmission, dopaminergic
response to amphetamine
heart morphogenesis
dopamine biosynthetic process from tyrosine
fatty acid metabolic process
sphingolipid metabolic process
heart development
visual perception
sensory perception of sound
learning
memory
mating behavior
locomotory behavior
regulation of heart contraction
response to water deprivation
response to light stimulus
response to herbicide
response to salt stress
anatomical structure morphogenesis
organ morphogenesis
response to zinc ion
multicellular organism aging
response to activity
aminergic neurotransmitter loading into synaptic vesicle
glycoside metabolic process
phthalate metabolic process
cerebral cortex development
response to nutrient levels
response to estradiol
response to lipopolysaccharide
isoquinoline alkaloid metabolic process
social behavior
cellular response to drug
response to isolation stress
response to immobilization stress
neurotransmitter biosynthetic process
terpene metabolic process
dopamine biosynthetic process
epinephrine biosynthetic process
norepinephrine biosynthetic process
catecholamine biosynthetic process
eye photoreceptor cell development
circadian sleep/wake cycle
eating behavior
response to peptide hormone
pigmentation
response to ethanol
response to ether
response to pyrethroid
embryonic camera-type eye morphogenesis
response to corticosterone
response to electrical stimulus
phytoalexin metabolic process
oxidation-reduction process
cellular response to manganese ion
cellular response to nicotine
cellular response to glucose stimulus
cellular response to growth factor stimulus

Function(s)

tyrosine 3-monooxygenase activity
protein binding
ferrous iron binding
ferric iron binding
amino acid binding
oxygen binding
enzyme binding
protein domain specific binding
tetrahydrobiopterin binding
dopamine binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR11001137.hg.1	NR_039834.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11001137.hg.1	TC11000059.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	TC1100006563.hg.1	ENST00000584128.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100006563.hg.1	NR_039834.1	Refseq
Affymetrix Human Clariom D Assay	TC1100006563.hg.1	ENST00000584128.1	Ensembl
Affymetrix Human Clariom D Assay	TC1100006563.hg.1	NR_039834.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100145829.hg.1	ENST00000584128.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1100145829.hg.1	NR_039834.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100145829.hg.1	ENST00000584128.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1100145829.hg.1	NR_039834.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100145829.hg.1	TC1100006563.hg.1	Clariom D TC