Hs04985767_s1

• Gene Symbol: ERN1
• Gene Name: endoplasmic reticulum to nucleus signaling 1
• Gene Aliases: IRE1, IRE1P, IRE1a, hIRE1p
• Chromosome Location: Chr.17: 64039142 - 64130819 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ERN1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_017024347.1	XP_016879836.1	22	7771		109
GenBank mRNA	AK124426.1	-	1	1227		109

More Information

• Set Membership: Amplicon length greater than or equal to 101, 3' Most, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Panther Classification:

Molecular Function -

endoribonuclease

Gene Ontology Categories:

Process(es)

endothelial cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA cleavage
mRNA catabolic process
protein phosphorylation
activation of signaling protein activity involved in unfolded protein response
cell cycle arrest
activation of JUN kinase activity
regulation of macroautophagy
positive regulation of RNA splicing
response to endoplasmic reticulum stress
cellular response to vascular endothelial growth factor stimulus
peptidyl-serine autophosphorylation
IRE1-mediated unfolded protein response
protein autophosphorylation
mRNA splicing, via endonucleolytic cleavage and ligation
mRNA endonucleolytic cleavage involved in unfolded protein response
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to glucose stimulus
RNA phosphodiester bond hydrolysis, endonucleolytic
positive regulation of endoplasmic reticulum unfolded protein response
insulin metabolic process
peptidyl-serine trans-autophosphorylation

Function(s)

magnesium ion binding
endoribonuclease activity
protein serine/threonine kinase activity
protein binding
ATP binding
enzyme binding
Hsp70 protein binding
identical protein binding
protein homodimerization activity
ADP binding
Hsp90 protein binding