Hs05028846_s1

Gene Symbol:

PRDX1 MMACHC

Gene Name:

peroxiredoxin 1

methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria

Gene Aliases:

MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2

cblC

Chromosome Location:

Chr.1: 45511035 - 45522890 on Build GRCh38

Chromosome Location:

Chr.1: 45500184 - 45511266 on Build GRCh38

Species:

Human

Species Specific ID (Flybase ID):

-

-

Assay Details

Gene Symbol: PRDX1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001202431.1	NP_001189360.1	6	919		86
	NM_002574.3	NP_002565.1	6	1136		86
	NM_181696.2	NP_859047.1	6	1110		86
	NM_181697.2	NP_859048.1	6	916		86
GenBank mRNA	AI912389.1	-	1			86
	AK131049.1	-	6	864		86
	BC007063.1	-	6	862	3961375	86
	BC021683.1	-	6	868	3681912	86
	X67951.1	-	6	855		86

Gene Symbol: MMACHC
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_005270724.4	XP_005270781.1	3			86
	XM_011541204.2	XP_011539506.1	4			86

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	AK129949.1	-		1734		Chr. 2 - 144126078 - 144127584 [-] on Build GRCh38	86

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, 3' Most, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PRDX1
Click here to find siRNAs for Gene MMACHC

Panther Classification:

Molecular Function -

peroxidase

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
skeletal system development
retina homeostasis
cell proliferation
removal of superoxide radicals
regulation of stress-activated MAPK cascade
erythrocyte homeostasis
natural killer cell mediated cytotoxicity
regulation of NF-kappaB import into nucleus
hydrogen peroxide catabolic process
cell redox homeostasis
oxidation-reduction process
cell-cell adhesion
cobalamin metabolic process
cobalamin biosynthetic process

Function(s)

peroxidase activity
protein binding
thioredoxin peroxidase activity
identical protein binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion
oxidoreductase activity
cobalamin binding
cyanocobalamin reductase (cyanide-eliminating) activity