Hs05050997_s1

• Gene Symbol: FURIN
• Gene Name: furin, paired basic amino acid cleaving enzyme
• Gene Aliases: FUR, PACE, PCSK3, SPC1
• Chromosome Location: Chr.15: 90868592 - 90883458 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: FURIN
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001289823.1	NP_001276752.1	16	3257		74
	NM_001289824.1	NP_001276753.1	16	3411		74
	NM_002569.3	NP_002560.1	16	3310		74
GenBank mRNA	BC008295.1	-	1	498		74
	BC012181.1	-	15	3080	4550620	74
	X17094.1	-	16	3247		74

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, 3' Most, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene FURIN

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

signal peptide processing
transforming growth factor beta receptor signaling pathway
aging
cell proliferation
negative regulation of endopeptidase activity
protein processing
peptide hormone processing
viral life cycle
viral protein processing
extracellular matrix disassembly
extracellular matrix organization
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
collagen catabolic process
nerve growth factor processing
negative regulation of low-density lipoprotein particle receptor catabolic process
nerve growth factor production
negative regulation of nerve growth factor production
negative regulation of transforming growth factor beta1 production
secretion by cell
regulation of protein catabolic process
peptide biosynthetic process
cellular protein metabolic process
regulation of low-density lipoprotein particle receptor biosynthetic process
positive regulation of membrane protein ectodomain proteolysis
regulation of endopeptidase activity

Function(s)

protease binding
endopeptidase activity
serine-type endopeptidase activity
serine-type endopeptidase inhibitor activity
protein binding
peptidase activity
peptide binding
metal ion binding
nerve growth factor binding