Hs05643142_s1

• Gene Symbol: SPI1
• Gene Name: Spi-1 proto-oncogene
• Gene Aliases: OF, PU.1, SFPI1, SPI-1, SPI-A
• Chromosome Location: Chr.11: 47354858 - 47395640 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: SPI1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_011520307.1	XP_011518609.1	2	837		111
	XM_017018173.1	XP_016873662.1	2	837		111

More Information

Additional Information:

This assay is in the 5'UTR region of the XM_011520307.1, XM_017018173.1 transcripts.

• Set Membership: Amplicon length greater than or equal to 101, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
lymphoid progenitor cell differentiation
transcription from RNA polymerase II promoter
lymphocyte differentiation
erythrocyte differentiation
macrophage differentiation
granulocyte differentiation
somatic stem cell population maintenance
myeloid dendritic cell differentiation
histone H3 acetylation
hypermethylation of CpG island
negative regulation of MHC class II biosynthetic process
regulation of erythrocyte differentiation
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anatomical structure regression
cellular response to ethanol
negative regulation of histone H4 acetylation
apoptotic process involved in patterning of blood vessels
positive regulation of pri-miRNA transcription from RNA polymerase II promoter

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
RNA binding
protein binding
NFAT protein binding