Hs06596636_m1

• Gene Symbol: MGMT
• Gene Name: O-6-methylguanine-DNA methyltransferase
• Gene Aliases: -
• Chromosome Location: Chr.10: 129467184 - 129770983 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MGMT
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_002412.4	NP_002403.2	1 - 2	109		74
GenBank mRNA	AK293593.1	-	1 - 2	79		74
	BC000824.1	-	1 - 2	37	3454207	74
	BI520029.1	-	1 - 2	91		74
	DC387686.1	-	1 - 2	103		74
	DC416206.1	-	1 - 2	109		74
	M29971.1	-	1 - 2	80		74

More Information

Additional Information:

This assay is in the 5'UTR region of the BC000824.1, M29971.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MGMT

Gene Ontology Categories:

Process(es)

DNA ligation
DNA methylation
DNA dealkylation involved in DNA repair
response to toxic substance
cellular response to oxidative stress
response to drug
negative regulation of apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to ethanol
response to folic acid
mammary gland epithelial cell differentiation
cellular response to organic cyclic compound
cellular response to ionizing radiation
positive regulation of double-strand break repair

Function(s)

DNA binding
damaged DNA binding
methylated-DNA-[protein]-cysteine S-methyltransferase activity
calcium ion binding
methyltransferase activity
DNA-methyltransferase activity