Mm00432437_m1

• Gene Symbol: Cdk5
• Gene Name: cyclin-dependent kinase 5
• Gene Aliases: AW048668, Crk6
• Chromosome Location: Chr.5: 24407597 - 24423591 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Cdk5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_007668.3	NP_031694.1	1 - 2	85		93
GenBank mRNA	AK051790.1	-	1 - 2	85		93
	BC052007.1	-	1 - 2	59	5706932	93
	D29678.1	-	1 - 2	94		93

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500002077.mm.1

Additional Information:

This assay is in the 5'UTR region of the AK051790.1,BC052007.1,D29678.1,NM_007668.3 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Kinase, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Cdk5

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

neuron migration
synaptic transmission, dopaminergic
protein phosphorylation
intracellular protein transport
exocytosis
nucleocytoplasmic transport
apoptotic process
cell cycle
cell-matrix adhesion
nervous system development
axonogenesis
synapse assembly
skeletal muscle tissue development
motor neuron axon guidance
associative learning
visual learning
response to wounding
Schwann cell development
phosphorylation
cell migration
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
sensory perception of pain
telencephalon development
cerebellum development
cerebellar cortex development
cerebellar cortex formation
hippocampus development
layer formation in cerebral cortex
central nervous system neuron development
cerebral cortex development
corpus callosum development
neuron differentiation
regulation of cell migration
negative regulation of axon extension
cortical actin cytoskeleton organization
forebrain development
neuron projection development
negative regulation of protein ubiquitination
negative regulation of synaptic plasticity
positive regulation of protein binding
receptor catabolic process
serine phosphorylation of STAT3 protein
synaptic transmission, glutamatergic
protein localization to synapse
response to cocaine
receptor clustering
positive regulation of neuron apoptotic process
regulated exocytosis
negative regulation of cell cycle
positive regulation of protein kinase activity
negative regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of calcium ion-dependent exocytosis
protein autophosphorylation
negative regulation of protein export from nucleus
behavioral response to cocaine
regulation of synaptic plasticity
synaptic vesicle endocytosis
rhythmic process
oligodendrocyte differentiation
neuron projection morphogenesis
dendrite morphogenesis
cell division
neuron apoptotic process
regulation of cell cycle
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
regulation of dendritic spine morphogenesis
calcium ion import
positive regulation of protein targeting to membrane
negative regulation of neuron death
positive regulation of receptor activity

Function(s)

nucleotide binding
p53 binding
protein kinase activity
protein serine/threonine kinase activity
cyclin-dependent protein serine/threonine kinase activity
ErbB-2 class receptor binding
protein binding
ATP binding
cytoskeletal protein binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
acetylcholine receptor activator activity
ErbB-3 class receptor binding
ephrin receptor binding
tau-protein kinase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500018889.mm.1	TC0500002077.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500018889.mm.1	NM_007668.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500018889.mm.1	NM_007668.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500018888.mm.1	TC0500002077.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500018888.mm.1	NM_007668.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500018888.mm.1	NM_007668.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0500018890.mm.1	TC0500002077.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500018890.mm.1	NM_007668.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500018890.mm.1	NM_007668.3	Refseq