Mm00432608_m1

• Gene Symbol: Ccr7
• Gene Name: chemokine (C-C motif) receptor 7
• Gene Aliases: CC-CKR-7, CCR-7, CD197, Cdw197, Cmkbr7, EBI1, Ebi1h
• Chromosome Location: Chr.11: 99144199 - 99155077 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ccr7
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_007719.2	NP_031745.2	1 - 2	91		104
GenBank mRNA	AK037965.1	-	1 - 2	92		104
	AK154349.1	-	1 - 2	92		104
	AK154736.1	-	1 - 2	92		104
	AK154849.1	-	1 - 2	92		104

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100003696.mm.1

Additional Information:

This assay is in the 5'UTR region of the AK037965.1,AK154349.1,AK154736.1,AK154849.1,NM_007719.2 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, G-protein coupled receptor, Mus musculus, Mouse Immune Response, 1700, Inventoried, Mouse_Immune_Response, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ccr7

Gene Ontology Categories:

Process(es)

establishment of T cell polarity
myeloid dendritic cell chemotaxis
lymphocyte chemotaxis across high endothelial venule
positive regulation of dendritic cell antigen processing and presentation
regulation of tolerance induction to self antigen
positive regulation of hypersensitivity
positive regulation of humoral immune response
chemotaxis
inflammatory response
immune response
signal transduction
G-protein coupled receptor signaling pathway
activation of JUN kinase activity
positive regulation of macrophage chemotaxis
positive regulation of T cell chemotaxis
actin cytoskeleton organization
response to lipopolysaccharide
regulation of interferon-gamma production
positive regulation of interleukin-12 production
positive regulation of tumor necrosis factor production
response to prostaglandin E
chemokine (C-C motif) ligand 19 signaling pathway
chemokine (C-C motif) ligand 21 signaling pathway
positive regulation of T cell proliferation
positive regulation of GTPase activity
negative thymic T cell selection
positive regulation of T-helper 1 cell differentiation
positive regulation of receptor-mediated endocytosis
lymph node development
regulation of interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
positive regulation of phagocytosis
positive regulation of T cell receptor signaling pathway
positive regulation of filopodium assembly
chemokine-mediated signaling pathway
cellular response to cytokine stimulus
response to nitric oxide
interleukin-12 secretion
positive regulation of neutrophil chemotaxis
lymphocyte migration into lymph node
mature conventional dendritic cell differentiation
negative regulation of leukocyte apoptotic process
positive regulation of cell motility
positive regulation of thymocyte migration
positive regulation of dendritic cell chemotaxis
positive regulation of immunological synapse formation
positive regulation of T cell costimulation
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
regulation of dendritic cell dendrite assembly

Function(s)

signal transducer activity
G-protein coupled receptor activity
chemokine receptor activity
protein binding
C-C chemokine receptor activity
chemokine (C-C motif) ligand 19 binding
chemokine (C-C motif) ligand 21 binding
C-C motif chemokine 19 receptor activity
C-C motif chemokine 21 receptor activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100034092.mm.1	NM_007719.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100034092.mm.1	NM_007719.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1100034092.mm.1	TC1100003696.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100034091.mm.1	NM_007719.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100034091.mm.1	NM_007719.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1100034091.mm.1	TC1100003696.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	876665	-	-