Mm00432880_mH

• Gene Symbol: Dnmt3a
• Gene Name: DNA methyltransferase 3A
• Gene Aliases: MmuIIIA
• Chromosome Location: Chr.12: 3804535 - 3914443 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Dnmt3a
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001271753.1	NP_001258682.1	16 - 17	2187		63
	NM_007872.4	NP_031898.1	16 - 17	2233		63
	NM_153743.4	NP_714965.1	11 - 12	1411		63
GenBank mRNA	AF068625.2	-	16 - 17	2137		63
	AF480164.1	-	11 - 12	1411		63
	AK077792.1	-	11 - 12	1376		63
	AK090132.1	-	16 - 17	2164		63
	AK147263.1	-	16 - 17	2187		63
	AK147627.1	-	16 - 17	2187		63
	AK147642.1	-	16 - 17	2187		63
	AK147676.1	-	16 - 17	2162		63
	AK157792.1	-	11 - 12	1382		63
	BC007466.1	-	16 - 17	2165	3492853	63

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1200000016.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Dnmt3a

Panther Classification:

Molecular Function -

DNA methyltransferase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
methylation-dependent chromatin silencing
regulation of gene expression by genetic imprinting
transcription, DNA-templated
regulation of transcription, DNA-templated
spermatogenesis
maintenance of DNA methylation
DNA methylation on cytosine within a CG sequence
positive regulation of cell death
chromatin modification
methylation
DNA methylation on cytosine
DNA methylation involved in embryo development
DNA methylation involved in gamete generation
hypermethylation of CpG island
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
cellular response to amino acid stimulus
C-5 methylation of cytosine

Function(s)

DNA binding
chromatin binding
DNA (cytosine-5-)-methyltransferase activity
protein binding
methyltransferase activity
transferase activity
identical protein binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1200000241.mm.1	NM_001271753.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1200000241.mm.1	NM_007872.4.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1200000241.mm.1	NM_007872.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1200000241.mm.1	NM_153743.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1200000241.mm.1	TC1200000016.mm.1	MTA TC