Mm00433958_m1

• Gene Symbol: Hnf4a
• Gene Name: hepatic nuclear factor 4, alpha
• Gene Aliases: HNF-4, Hnf4, Hnf4alpha, MODY1, Nr2a1, Tcf14
• Chromosome Location: Chr.2: 163506809 - 163572907 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Hnf4a
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008261.2	NP_032287.2	1 - 2	229		82
GenBank mRNA	AK143948.1	-	1 - 2	254		82
	BC039220.1	-	1 - 2	229	4238842	82
	D29015.1	-	1 - 2	156		82
	EF193393.1	-	1 - 2	54		82

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0200002489.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Nuclear Receptor, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Hnf4a

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
ornithine metabolic process
lipid metabolic process
acyl-CoA metabolic process
xenobiotic metabolic process
establishment of tissue polarity
sex differentiation
blood coagulation
negative regulation of cell proliferation
response to glucose
regulation of gastrulation
regulation of lipid metabolic process
signal transduction involved in regulation of gene expression
cell differentiation
negative regulation of cell growth
regulation of microvillus assembly
negative regulation of protein import into nucleus, translocation
negative regulation of tyrosine phosphorylation of Stat5 protein
glucose homeostasis
steroid hormone mediated signaling pathway
negative regulation of sequence-specific DNA binding transcription factor activity
cell-cell junction organization
positive regulation of gluconeogenesis
positive regulation of fatty acid biosynthetic process
positive regulation of transcription, DNA-templated
negative regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
regulation of insulin secretion
lipid homeostasis
phospholipid homeostasis
SMAD protein signal transduction
triglyceride homeostasis
negative regulation of activation of JAK2 kinase activity
positive regulation of cholesterol homeostasis

Function(s)

fatty-acyl-CoA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
receptor binding
fatty acid binding
protein binding
transcription factor binding
zinc ion binding
palmitoyl-CoA hydrolase activity
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
repressing transcription factor binding