Mm00434225_m1

• Gene Symbol: Il18
• Gene Name: interleukin 18
• Gene Aliases: Igif, Il-18
• Chromosome Location: Chr.9: 50554705 - 50581841 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Il18
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008360.1	NP_032386.1	4 - 5	385		104
GenBank mRNA	AY157834.1	-	4 - 5	378		104
	AY157835.1	-	4 - 5	378		104
	AY362457.1	-	3 - 4	230		104
	AY916131.1	-	3 - 4	221		104
	BC024384.1	-	4 - 5	379	4988988	104
	D49949.1	-	4 - 5	385		104
	DQ316604.1	-	3 - 4	221		104
	U66244.1	-	3 - 4	221		104

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0900000599.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, Mouse Chemokine Panel, Mouse Tumor Metastasis Panel, Mouse Immune Response, 1700, Inventoried, Mouse_Immune_Response, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Il18

Panther Classification:

Molecular Function -

interleukin superfamily

Gene Ontology Categories:

Process(es)

MAPK cascade
angiogenesis
response to hypoxia
inflammatory response
immune response
extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of gene expression
positive regulation of smooth muscle cell migration
natural killer cell activation
regulation of cell adhesion
sleep
lipopolysaccharide-mediated signaling pathway
positive regulation of chemokine production
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of natural killer cell proliferation
positive regulation of superoxide anion generation
positive regulation of collagen biosynthetic process
negative regulation of neutrophil apoptotic process
T-helper 1 type immune response
interferon-gamma biosynthetic process
positive regulation of activated T cell proliferation
interleukin-13 biosynthetic process
positive regulation of NF-kappaB import into nucleus
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of apoptotic process
positive regulation of vascular permeability
positive regulation of neuron apoptotic process
negative regulation of myoblast differentiation
positive regulation of smooth muscle cell proliferation
negative regulation of peptidyl-tyrosine phosphorylation
detection of mechanical stimulus involved in sensory perception of pain
positive regulation of NK T cell proliferation
cellular response to lipopolysaccharide
cellular response to peptide hormone stimulus
cellular response to organic cyclic compound
positive regulation of male germ cell proliferation
positive regulation of blood vessel remodeling

Function(s)

cytokine activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	354902	-	-