Mm00435295_g1

• Gene Symbol: Npc1
• Gene Name: Niemann-Pick type C1
• Gene Aliases: A430089E03Rik, C85354, D18Ertd139e, D18Ertd723e, lcsd, nmf164, spm
• Chromosome Location: Chr.18: 12189694 - 12236386 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Npc1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008720.2	NP_032746.2	15 - 16	2526		78
GenBank mRNA	AF003348.1	-	15 - 16	2503		78
	AK154282.1	-	15 - 16	2446		78
	AK155379.1	-	15 - 16	2446		78
	BC052437.1	-	15 - 16	2526	6405214	78
	BC054539.1	-	15 - 16	2526	6405214	78

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1800000994.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Npc1

Gene Ontology Categories:

Process(es)

protein glycosylation
lipid metabolic process
endocytosis
autophagy
adult walking behavior
steroid metabolic process
cholesterol metabolic process
negative regulation of macroautophagy
cholesterol transport
membrane raft organization
cholesterol efflux
response to drug
cholesterol homeostasis
response to cadmium ion
viral entry into host cell
negative regulation of cell death
cellular response to steroid hormone stimulus
cellular response to low-density lipoprotein particle stimulus
establishment of protein localization to membrane
positive regulation of cholesterol homeostasis

Function(s)

protein binding
hedgehog receptor activity
cholesterol binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1800007384.mm.1	NM_008720.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1800007384.mm.1	NM_008720.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1800007384.mm.1	TC1800000994.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1800007383.mm.1	NM_008720.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1800007383.mm.1	NM_008720.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1800007383.mm.1	TC1800000994.mm.1	MTA TC