Mm00435659_m1

• Gene Symbol: Pik3ca
• Gene Name: phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
• Gene Aliases: 6330412C24Rik, caPI3K, p110, p110alpha
• Chromosome Location: Chr.3: 32397055 - 32468486 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pik3ca
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008839.2	NP_032865.2	4 - 5	1118		117
GenBank mRNA	AK051885.1	-	4 - 5	751		117
	BC089038.1	-	4 - 5	1118	30692343	117
	BC130228.1	-	4 - 5	1067	40141870	117
	U03279.1	-	4 - 5	1063		117

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0300000221.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pik3ca

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

angiogenesis
liver development
adaptive immune response
glucose metabolic process
protein phosphorylation
inflammatory response
phosphatidylinositol 3-kinase signaling
phosphorylation
platelet activation
positive regulation of peptidyl-serine phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
regulation of multicellular organism growth
regulation of cellular respiration
protein kinase B signaling
negative regulation of neuron apoptotic process
hypomethylation of CpG island
innate immune response
positive regulation of protein kinase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
cell chemotaxis
adipose tissue development
cellular response to glucose stimulus
energy homeostasis
mitophagy in response to mitochondrial depolarization
negative regulation of fibroblast apoptotic process
regulation of genetic imprinting
negative regulation of anoikis

Function(s)

nucleotide binding
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
1-phosphatidylinositol-3-kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphotransferase activity, alcohol group as acceptor
protein kinase activator activity
1-phosphatidylinositol-4-phosphate 3-kinase activity
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0300001231.mm.1	NM_008839.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300001231.mm.1	NM_008839.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0300001231.mm.1	TC0300000221.mm.1	MTA TC