Mm00436262_m1

• Gene Symbol: Rara
• Gene Name: retinoic acid receptor, alpha
• Gene Aliases: Nr1b1, RAR, RARalpha1
• Chromosome Location: Chr.11: 98927809 - 98974942 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Rara
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001177302.1	NP_001170773.1	3 - 4	866		82
	NM_001177303.1	NP_001170774.1	2 - 3	611		82
	NM_009024.2	NP_033050.2	2 - 3	733		82
GenBank mRNA	AB221572.1	-	1 - 2	180		82
	AK042163.1	-	2 - 3	612		82
	AK154623.1	-	2 - 3	706		82
	BC010216.1	-	2 - 3	731	3498142	82
	BC040383.1	-	3 - 4	866		82
	BC090396.1	-	1 - 2	277		82
	CT010231.1	-	1 - 2	176		82
	S56656.1	-	2 - 3	713		82

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100001587.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Nuclear Receptor, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Rara

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ureteric bud development
neural tube closure
glandular epithelial cell development
outflow tract septum morphogenesis
growth plate cartilage development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein phosphorylation
signal transduction
germ cell development
spermatogenesis
positive regulation of cell proliferation
negative regulation of cell proliferation
male gonad development
positive regulation of gene expression
negative regulation of gene expression
positive regulation of phosphatidylinositol 3-kinase signaling
negative regulation of translation
regulation of granulocyte differentiation
negative regulation of granulocyte differentiation
embryonic camera-type eye development
regulation of myelination
response to retinoic acid
negative regulation of interferon-gamma production
negative regulation of tumor necrosis factor production
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-5 production
multicellular organism growth
regulation of apoptotic process
negative regulation of apoptotic process
apoptotic cell clearance
steroid hormone mediated signaling pathway
regulation of phosphatidylinositol 3-kinase activity
response to ethanol
negative regulation of cell differentiation
positive regulation of T-helper 2 cell differentiation
positive regulation of neuron differentiation
positive regulation of cell cycle
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of translational initiation
regulation of synaptic plasticity
retinoic acid receptor signaling pathway
positive regulation of binding
positive regulation of protein kinase B signaling
ventricular cardiac muscle cell differentiation
Sertoli cell fate commitment
limb development
face development
bone development
trachea cartilage development
chondroblast differentiation
negative regulation of cartilage development
positive regulation of ERK1 and ERK2 cascade
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to estrogen stimulus

Function(s)

translation repressor activity, nucleic acid binding
regulatory region DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region DNA binding
retinoic acid binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
retinoic acid receptor activity
transcription coactivator activity
transcription corepressor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
receptor binding
protein binding
transcription factor binding
drug binding
zinc ion binding
enzyme binding
protein domain specific binding
chromatin DNA binding
phosphatidylinositol 3-kinase regulator activity
histone deacetylase binding
protein kinase B binding
sequence-specific DNA binding
transcription regulatory region DNA binding
retinoic acid-responsive element binding
metal ion binding
protein heterodimerization activity
mRNA 5'-UTR binding
protein kinase A binding
alpha-actinin binding