Mm00436953_m1

• Gene Symbol: Tgfb2
• Gene Name: transforming growth factor, beta 2
• Gene Aliases: BB105277, Tgf-beta2, Tgfb-2
• Chromosome Location: Chr.1: 186622787 - 186709033 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Tgfb2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_009367.3	NP_033393.2	2 - 3	1730		63
GenBank mRNA	AK141552.1	-	3 - 4	1112		63
	AK159690.1	-	2 - 3	294		63
	BC011170.1	-	2 - 3	638	4035366	63
	X57413.1	-	2 - 3	1729		63

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0100003754.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Tgfb2

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

cell morphogenesis
skeletal system development
cartilage condensation
blood vessel development
eye development
response to hypoxia
epithelial to mesenchymal transition
hair follicle development
blood vessel remodeling
heart morphogenesis
outflow tract morphogenesis
heart valve morphogenesis
cardiac left ventricle morphogenesis
cardiac right ventricle morphogenesis
protein phosphorylation
cell cycle arrest
transforming growth factor beta receptor signaling pathway
SMAD protein import into nucleus
axon guidance
heart development
cell death
positive regulation of cell proliferation
negative regulation of cell proliferation
glial cell migration
cardioblast differentiation
positive regulation of gene expression
positive regulation of epithelial cell migration
negative regulation of alkaline phosphatase activity
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of macrophage cytokine production
positive regulation of phosphatidylinositol 3-kinase signaling
cell growth
cell migration
signal transduction by protein phosphorylation
hemopoiesis
extracellular matrix organization
collagen fibril organization
positive regulation of cell growth
negative regulation of cell growth
positive regulation of cell migration
hair follicle morphogenesis
activation of protein kinase activity
response to progesterone
positive regulation of stress-activated MAPK cascade
regulation of transforming growth factor beta2 production
positive regulation of cell adhesion mediated by integrin
intracellular signal transduction
growth
wound healing
regulation of cell proliferation
dopamine biosynthetic process
response to drug
catagen
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
regulation of MAPK cascade
positive regulation of neuron apoptotic process
response to estrogen
cell-cell junction organization
negative regulation of keratinocyte differentiation
positive regulation of integrin biosynthetic process
positive regulation of cell cycle
positive regulation of heart contraction
somatic stem cell division
neuron fate commitment
neuron development
embryonic neurocranium morphogenesis
negative regulation of epithelial cell proliferation
positive regulation of protein secretion
negative regulation of immune response
negative regulation of release of sequestered calcium ion into cytosol
positive regulation of cell division
positive regulation of catagen
positive regulation of cardioblast differentiation
cardiac muscle cell proliferation
cardiac epithelial to mesenchymal transition
pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
ventricular septum morphogenesis
negative regulation of cartilage development
positive regulation of activation-induced cell death of T cells
extrinsic apoptotic signaling pathway
regulation of extracellular matrix organization
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

beta-amyloid binding
receptor signaling protein serine/threonine kinase activity
receptor binding
type II transforming growth factor beta receptor binding
cytokine activity
transforming growth factor beta receptor binding
protein binding
growth factor activity
type III transforming growth factor beta receptor binding
protein homodimerization activity
protein heterodimerization activity
protein N-terminus binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0100030760.mm.1	NM_009367.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0100030760.mm.1	TC0100003754.mm.1	MTA TC