Mm00437268_g1

• Gene Symbol: Nr1h2
• Gene Name: nuclear receptor subfamily 1, group H, member 2
• Gene Aliases: AI194859, LXR, LXRB, LXRbeta, NER1, OR-1, RIP15, UR, Unr, Unr2
• Chromosome Location: Chr.7: 44549616 - 44553969 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Nr1h2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001285517.1	NP_001272446.1	8 - 9	1291		71
	NM_001285518.1	NP_001272447.1	8 - 9	1285		71
	NM_001285519.1	NP_001272448.1	8 - 9	1282		71
	NM_009473.3	NP_033499.1	8 - 9	1298		71
GenBank mRNA	AK077620.1	-	8 - 9	1264		71
	AK134489.1	-	8 - 9	1248		71
	AK156777.1	-	8 - 9	1266		71
	AK177488.1	-	1 - 2	49		71
	AK194055.1	-	1 - 2	49		71
	BC066025.1	-	8 - 9	1249	6829527	71
	BC106148.1	-	7 - 8	1018		71
	EU869275.2	-	5 - 6	1277		71
	U09419.1	-	7 - 8	1116		71

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0700002970.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Nuclear Receptor, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Nr1h2

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of gene expression
negative regulation of gene expression
positive regulation of triglyceride biosynthetic process
positive regulation of cholesterol efflux
positive regulation of lipid storage
negative regulation of cholesterol storage
intracellular receptor signaling pathway
positive regulation of cellular protein metabolic process
negative regulation of lipid transport
positive regulation of cholesterol transport
cholesterol homeostasis
steroid hormone mediated signaling pathway
cellular lipid metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
retinoic acid receptor signaling pathway
negative regulation of pinocytosis
positive regulation of lipoprotein lipase activity
lipid homeostasis
positive regulation of high-density lipoprotein particle assembly
positive regulation of pancreatic juice secretion
positive regulation of secretion of lysosomal enzymes
regulation of cholesterol homeostasis

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
apolipoprotein A-I receptor binding
sequence-specific DNA binding
metal ion binding
retinoid X receptor binding
ATPase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0700026382.mm.1	TC0700002970.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0700026382.mm.1	NM_001285517.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0700026382.mm.1	NM_001285518.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0700026382.mm.1	NM_001285519.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0700026382.mm.1	NM_009473.3	Refseq