Mm00438421_g1

• Gene Symbol: Dkk1
• Gene Name: dickkopf homolog 1 (Xenopus laevis)
• Gene Aliases: mdkk-1
• Chromosome Location: Chr.19: 30545876 - 30549496 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Dkk1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010051.3	NP_034181.2	1 - 2	368		67
GenBank mRNA	AF030433.1	-	1 - 2	287		67
	AK141693.1	-	1 - 2	392		67
	AK144119.1	-	1 - 2	394		67
	BC050189.1	-	1 - 2	368	30022799	67
	JN966751.1	-	1 - 2	421		67

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1900001360.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, 1700, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Dkk1

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis involved in differentiation
endoderm formation
mesoderm formation
hair follicle development
regulation of receptor internalization
multicellular organism development
endoderm development
Wnt signaling pathway
regulation of Wnt signaling pathway
negative regulation of Wnt signaling pathway
embryonic limb morphogenesis
negative regulation of BMP signaling pathway
forebrain development
negative regulation of protein complex assembly
response to retinoic acid
negative regulation of peptidyl-serine phosphorylation
negative regulation of mesodermal cell fate specification
regulation of endodermal cell fate specification
negative regulation of skeletal muscle tissue development
head morphogenesis
face morphogenesis
negative regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
extracellular negative regulation of signal transduction
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
negative regulation of receptor activity
negative regulation of cardiac muscle cell differentiation

Function(s)

protein binding
receptor antagonist activity
low-density lipoprotein particle receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1900012070.mm.1	NM_010051.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1900012070.mm.1	NM_010051.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1900012070.mm.1	TC1900001360.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1900012071.mm.1	NM_010051.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1900012071.mm.1	NM_010051.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1900012071.mm.1	TC1900001360.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	413654	-	-