Mm00438720_m1

• Gene Symbol: Epas1
• Gene Name: endothelial PAS domain protein 1
• Gene Aliases: HIF-2alpha, HIF2A, HLF, HRF, MOP2, bHLHe73
• Chromosome Location: Chr.17: 86753864 - 86833410 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Epas1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010137.3	NP_034267.3	10 - 11	1863		103
GenBank mRNA	AF045160.1	-	10 - 11	1627		103
	AK136911.1	-	10 - 11	1867		103
	AK141185.1	-	10 - 11	1598		103
	AK158430.1	-	10 - 11	2027		103
	BC057870.1	-	10 - 11	1585	5032291	103
	D89787.1	-	10 - 11	1825		103
	U81983.1	-	10 - 11	1546		103

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700001299.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Epas1

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

angiogenesis
response to hypoxia
embryonic placenta development
blood vessel remodeling
regulation of heart rate
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
response to oxidative stress
mitochondrion organization
signal transduction
multicellular organism development
visual perception
hemopoiesis
cell differentiation
erythrocyte differentiation
lung development
norepinephrine metabolic process
surfactant homeostasis
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
positive regulation of transcription from RNA polymerase II promoter
cell maturation
myoblast fate commitment
iron ion homeostasis
cellular response to hypoxia

Function(s)

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
protein binding
transcription factor binding
histone acetyltransferase binding
sequence-specific DNA binding
protein heterodimerization activity
protein dimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700011852.mm.1	NM_010137.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011852.mm.1	NM_010137.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1700011852.mm.1	TC1700001299.mm.1	MTA TC