Mm00443243_m1 Best Coverage

• Gene Symbol: Tek
• Gene Name: endothelial-specific receptor tyrosine kinase
• Gene Aliases: AA517024, Cd202b, Hyk, STK1, Tie-2, Tie2
• Chromosome Location: Chr.4: 94739289 - 94874976 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Tek
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001290549.1	NP_001277478.1	8 - 9	1532		76
	NM_001290551.1	NP_001277480.1	7 - 8	1379		76
	NM_013690.3	NP_038718.2	8 - 9	1532		76
GenBank mRNA	BC050824.1	-	7 - 8	1373	6333576	76
	D13738.1	-	8 - 9	1534		76
	S67051.1	-	9 - 10	1195		76
	X67553.1	-	8 - 9	1303		76
	X71426.1	-	9 - 10	1266		76

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0400000952.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protein Kinase, Mammalian Gene Collection, Recommended Assay, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Tek

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

angiogenesis
patterning of blood vessels
vasculogenesis
positive regulation of protein phosphorylation
endothelial cell proliferation
regulation of endothelial cell proliferation
sprouting angiogenesis
positive regulation of cytokine secretion involved in immune response
protein phosphorylation
cell-matrix adhesion
transmembrane receptor protein tyrosine kinase signaling pathway
heart development
positive regulation of endothelial cell migration
positive regulation of phosphatidylinositol 3-kinase signaling
phosphorylation
single organismal cell-cell adhesion
negative regulation of angiogenesis
peptidyl-tyrosine phosphorylation
hemopoiesis
regulation of cell migration
positive regulation of vascular endothelial growth factor receptor signaling pathway
response to retinoic acid
regulation of establishment or maintenance of cell polarity
positive regulation of peptidyl-serine phosphorylation
substrate adhesion-dependent cell spreading
intracellular signal transduction
positive regulation of protein import into nucleus
negative regulation of apoptotic process
positive regulation of phosphatidylinositol 3-kinase activity
response to estrogen
regulation of angiogenesis
positive regulation of angiogenesis
positive regulation of cell adhesion
protein autophosphorylation
Tie signaling pathway
protein oligomerization
positive regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
heart trabecula formation
positive regulation of ERK1 and ERK2 cascade
regulation of NIK/NF-kappaB signaling
positive regulation of intracellular signal transduction
positive regulation of actin cytoskeleton reorganization
negative regulation of endothelial cell apoptotic process

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
growth factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0400006293.mm.1	NM_013690.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0400006293.mm.1	TC0400000952.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0400006294.mm.1	NM_013690.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0400006294.mm.1	TC0400000952.mm.1	MTA TC