Mm00443974_m1

• Gene Symbol: Itgb3
• Gene Name: integrin beta 3
• Gene Aliases: CD61, GP3A, INGRB3
• Chromosome Location: Chr.11: 104608000 - 104670490 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Itgb3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_016780.2	NP_058060.2	4 - 5	700		65
GenBank mRNA	AF026509.1	-	4 - 5	644		65
	AK157958.1	-	4 - 5	646		65
	BC125518.1	-	4 - 5	700	40130033	65
	BC125520.1	-	4 - 5	700	40130035	65

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100001730.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Itgb3

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

positive regulation of endothelial cell proliferation
positive regulation of leukocyte migration
protein folding
cellular calcium ion homeostasis
cell-substrate junction assembly
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of endothelial cell migration
negative regulation of macrophage derived foam cell differentiation
positive regulation of fibroblast migration
negative regulation of lipid storage
smooth muscle cell migration
positive regulation of smooth muscle cell migration
cell growth
cell migration
platelet activation
regulation of cell migration
positive regulation of cell migration
cell-substrate adhesion
activation of protein kinase activity
negative regulation of lipid transport
positive regulation of cell adhesion mediated by integrin
positive regulation of osteoblast proliferation
heterotypic cell-cell adhesion
substrate adhesion-dependent cell spreading
apolipoprotein A-I-mediated signaling pathway
positive regulation of MAPK cascade
positive regulation of osteoclast differentiation
negative regulation of low-density lipoprotein particle receptor biosynthetic process
positive regulation of angiogenesis
positive regulation of bone resorption
viral entry into host cell
positive regulation of smooth muscle cell proliferation
cell projection morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of lipoprotein metabolic process
negative chemotaxis
regulation of release of sequestered calcium ion into cytosol
angiogenesis involved in wound healing
negative regulation of cell death
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
positive regulation of glomerular mesangial cell proliferation
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway

Function(s)

fibronectin binding
protease binding
protein disulfide isomerase activity
receptor activity
integrin binding
protein binding
peptide binding
identical protein binding
vascular endothelial growth factor receptor 2 binding
cell adhesion molecule binding
extracellular matrix binding
fibrinogen binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100016365.mm.1	NM_016780.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1100016365.mm.1	NM_016780.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1100016365.mm.1	TC1100001730.mm.1	MTA TC