Mm00445186_m1

• Gene Symbol: Cftr
• Gene Name: cystic fibrosis transmembrane conductance regulator
• Gene Aliases: AW495489, Abcc7
• Chromosome Location: Chr.6: 18170262 - 18322774 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Cftr
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_021050.2	NP_066388.1	6 - 7	878		108
GenBank mRNA	AK033621.1	-	6 - 7	796		108
	M60493.1	-	6 - 7	879		108
	M69298.1	-	6 - 7			108

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0600000145.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Ion Channel, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Cftr

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter

Gene Ontology Categories:

Process(es)

cholesterol biosynthetic process
transport
ion transport
chloride transport
water transport
bicarbonate transport
iodide transport
cholesterol transport
transepithelial chloride transport
lung development
vasodilation
positive regulation of vasodilation
sperm capacitation
intracellular pH elevation
transmembrane transport
membrane hyperpolarization
cellular response to cAMP
chloride transmembrane transport
positive regulation of voltage-gated chloride channel activity

Function(s)

nucleotide binding
chloride channel activity
channel-conductance-controlling ATPase activity
protein binding
ATP binding
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
hydrolase activity
ATPase activity
chloride channel inhibitor activity
enzyme binding
PDZ domain binding
ATPase activity, coupled to transmembrane movement of substances

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0600001022.mm.1	TC0600000145.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0600001022.mm.1	NM_021050.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0600001022.mm.1	NM_021050.2	Refseq