Mm00447454_m1

• Gene Symbol: Hnf1b
• Gene Name: HNF1 homeobox B
• Gene Aliases: HNF-1-beta, HNF-1B, HNF-1Beta, Hnf1beta, LFB3, Tcf-2, Tcf2, vHNF1
• Chromosome Location: Chr.11: 83850209 - 83905917 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Hnf1b
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001291268.1	NP_001278197.1	3 - 4	910		61
	NM_001291269.1	NP_001278198.1	3 - 4	619		61
	NM_009330.3	NP_033356.2	3 - 4	988		61
GenBank mRNA	AB008174.1	-	3 - 4	808		61
	AB008175.1	-	3 - 4	730		61
	AB008176.1	-	3 - 4	808		61
	AB008177.1	-	3 - 4	730		61
	AB052659.1	-	3 - 4	808		61
	AK004837.2	-	3 - 4	989		61
	AK019258.1	-	3 - 4	542		61
	BC025189.1	-	3 - 4	619	5044299	61
	X55842.1	-	3 - 4	808		61

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100001271.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Hnf1b

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
endoderm formation
endodermal cell fate specification
kidney development
inner cell mass cell differentiation
liver development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
Notch signaling pathway
endoderm development
response to glucose
anterior/posterior pattern specification
positive regulation of gene expression
insulin secretion
regulation of Wnt signaling pathway
hindbrain development
endocrine pancreas development
circadian regulation of gene expression
regulation of pronephros size
pronephric nephron tubule development
regulation of endodermal cell fate specification
negative regulation of apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic morphogenesis
branching morphogenesis of an epithelial tube
pronephros development
genitalia development
epithelial cell proliferation
positive regulation of transcription initiation from RNA polymerase II promoter
epithelium development
ureteric bud elongation
kidney morphogenesis
hepatoblast differentiation
negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis
protein-DNA complex assembly
regulation of branch elongation involved in ureteric bud branching
mesonephric tubule development
nephric duct development
mesonephric duct development
nephric duct formation
mesonephric duct formation
negative regulation of mesenchymal cell apoptotic process involved in metanephros development

Function(s)

core promoter proximal region DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein complex binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100011913.mm.1	NM_009330.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1100011913.mm.1	TC1100001271.mm.1	MTA TC