Mm00459769_m1

• Gene Symbol: Egln1
• Gene Name: egl-9 family hypoxia-inducible factor 1
• Gene Aliases: AI503754, C1orf12, HIF-PH2, HPH-2, Hif-p4h-2, ORF13, Phd2, SM-20
• Chromosome Location: Chr.8: 124908586 - 124949319 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Egln1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_053207.2	NP_444437.2	2 - 3	1140		100
GenBank mRNA	AF453878.1	-	2 - 3	329		100
	AJ310546.1	-	2 - 3	843		100
	BC006903.1	-	2 - 3	140	3600175	100
	BC083146.1	-	2 - 3	447		100

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0800003178.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Egln1

Gene Ontology Categories:

Process(es)

response to hypoxia
peptidyl-proline hydroxylation to 4-hydroxy-L-proline
negative regulation of cAMP catabolic process
oxygen homeostasis
negative regulation of sequence-specific DNA binding transcription factor activity
regulation of angiogenesis
negative regulation of cyclic-nucleotide phosphodiesterase activity
cardiac muscle tissue morphogenesis
oxidation-reduction process
heart trabecula formation
ventricular septum morphogenesis
labyrinthine layer development
response to nitric oxide

Function(s)

iron ion binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
enzyme binding
L-ascorbic acid binding
peptidyl-proline dioxygenase activity
peptidyl-proline 4-dioxygenase activity
metal ion binding
dioxygenase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0800024444.mm.1	NM_053207.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0800024444.mm.1	NM_053207.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0800024444.mm.1	TC0800003178.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0800024441.mm.1	NM_053207.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0800024441.mm.1	NM_053207.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0800024441.mm.1	TC0800003178.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0800024442.mm.1	NM_053207.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0800024442.mm.1	NM_053207.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0800024442.mm.1	TC0800003178.mm.1	MTA TC