Mm00466506_m1

• Gene Symbol: Raf1
• Gene Name: v-raf-leukemia viral oncogene 1
• Gene Aliases: 6430402F14Rik, AA990557, BB129353, Craf1, D830050J10Rik, Raf-1, c-Raf, v-Raf
• Chromosome Location: Chr.6: 115618573 - 115677129 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Raf1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_029780.3	NP_084056.1	5 - 6	1005		90
GenBank mRNA	AB057655.1	-	4 - 5	550		90
	AB057663.2	-	5 - 6	775		90
	AK036317.1	-	5 - 6	892		90
	AK141745.1	-	5 - 6	1006		90
	AK148327.1	-		68		90
	BC015273.1	-	5 - 6	884	4222659	90
	BC056439.1	-	5 - 6	924		90
	BC092040.1	-	5 - 6	870	2645313	90

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0600002955.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Apoptosis, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Raf1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
response to hypoxia
cellular glucose homeostasis
positive regulation of protein phosphorylation
protein phosphorylation
signal transduction
negative regulation of cell proliferation
phosphorylation
cell differentiation
negative regulation of protein complex assembly
positive regulation of peptidyl-serine phosphorylation
somatic stem cell population maintenance
intracellular signal transduction
insulin secretion involved in cellular response to glucose stimulus
response to muscle stretch
negative regulation of apoptotic process
intermediate filament cytoskeleton organization
positive regulation of transcription from RNA polymerase II promoter
neurotrophin TRK receptor signaling pathway
death-inducing signaling complex assembly
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
receptor signaling protein activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Ras GTPase binding
mitogen-activated protein kinase kinase binding
identical protein binding
metal ion binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0600022704.mm.1	TC0600002955.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0600022704.mm.1	NM_029780.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0600022704.mm.1	NM_029780.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0600022705.mm.1	TC0600002955.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0600022705.mm.1	NM_029780.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0600022705.mm.1	NM_029780.3	Refseq