Mm00468529_g1

• Gene Symbol: Hcls1
• Gene Name: hematopoietic cell specific Lyn substrate 1
• Gene Aliases: AW213261, HS1
• Chromosome Location: Chr.16: 36934983 - 36963214 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Hcls1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008225.2	NP_032251.2	7 - 8	661		82
GenBank mRNA	AK088723.1	-	7 - 8	643		82
	BC007469.1	-	7 - 8	631	3593456	82
	D42120.1	-	7 - 8	592		82
	X84797.1	-	7 - 8	629		82

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1600000529.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Hcls1

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein, cytoskeletal protein, non-motor actin binding protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
response to hormone
positive regulation of phosphatidylinositol 3-kinase signaling
actin filament polymerization
erythrocyte differentiation
regulation of actin filament polymerization
positive regulation of granulocyte differentiation
positive regulation of peptidyl-serine phosphorylation
positive regulation of tyrosine phosphorylation of STAT protein
positive regulation of transcription factor import into nucleus
positive regulation of macrophage differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of protein kinase B signaling
cellular response to cytokine stimulus
negative regulation of leukocyte apoptotic process

Function(s)

RNA polymerase II transcription factor binding
actin binding
protein binding
SH3 domain binding
protein kinase binding
protein complex binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1600004994.mm.1	NM_008225.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1600004994.mm.1	NM_008225.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1600004994.mm.1	TC1600000529.mm.1	MTA TC