Mm00468940_m1

• Gene Symbol: Shc1
• Gene Name: src homology 2 domain-containing transforming protein C1
• Gene Aliases: Shc, ShcA, p66, p66shc
• Chromosome Location: Chr.3: 89418481 - 89430029 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Shc1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011368.5	NP_035498.2	1 - 2	166		52
GenBank mRNA	AK049357.1	-	1 - 2	139		52
	BC036172.1	-	1 - 2	117	4988907	52
	U15784.1	-	1 - 2	56		52

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0300000763.mm.1

Additional Information:

This assay is in the 5'UTR region of the AK049357.1,BC036172.1,NM_011368.5,U15784.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Shc1

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
angiogenesis
signal transduction
epidermal growth factor receptor signaling pathway
heart development
aging
insulin receptor signaling pathway
single organismal cell-cell adhesion
actin cytoskeleton organization
neuron differentiation
neuron projection development
actin cytoskeleton reorganization
intracellular signal transduction
regulation of growth
regulation of cell proliferation
positive regulation of DNA replication
positive regulation of vasoconstriction
positive regulation of smooth muscle cell proliferation

Function(s)

phosphotyrosine binding
epidermal growth factor receptor binding
insulin receptor binding
insulin-like growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
protein kinase binding
receptor tyrosine kinase binding
protein complex binding
ephrin receptor binding
phosphoprotein binding
protein phosphatase 2A binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0300005749.mm.1	NM_011368.5.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300005749.mm.1	NM_011368.5	Refseq
Affymetrix Mouse Clariom S Array	PSR0300005749.mm.1	TC0300000763.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300005755.mm.1	NM_001113331.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300005755.mm.1	NM_001113331.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0300005755.mm.1	NM_011368.5.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300005755.mm.1	NM_011368.5	Refseq
Affymetrix Mouse Clariom S Array	PSR0300005755.mm.1	TC0300000763.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	308913	-	-