Mm00476558_m1

• Gene Symbol: Nthl1
• Gene Name: nth (endonuclease III)-like 1 (E.coli)
• Gene Aliases: Nth1, Octs3
• Chromosome Location: Chr.17: 24632682 - 24638838 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Nthl1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008743.2	NP_032769.2	3 - 4	582		72
GenBank mRNA	AB006812.1	-	3 - 4	528		72
	AK033701.1	-	3 - 4	1590		72
	AV377313.2	-	1 - 2	170		72
	BC138852.1	-	3 - 4	545	8861874	72
	BC138855.1	-	3 - 4	545	8861877	72
	BC145443.1	-	3 - 4	454		72
	CX565655.1	-	3 - 4	561		72
	Y09688.1	-	3 - 4	554		72

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700000346.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Nthl1

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
DNA repair
base-excision repair
base-excision repair, AP site formation
nucleotide-excision repair, DNA incision, 5'-to lesion
cellular response to DNA damage stimulus
metabolic process
mitophagy in response to mitochondrial depolarization

Function(s)

purine-specific mismatch base pair DNA N-glycosylase activity
DNA binding
double-stranded DNA binding
catalytic activity
DNA-(apurinic or apyrimidinic site) lyase activity
uracil DNA N-glycosylase activity
hydrolase activity
hydrolase activity, acting on glycosyl bonds
lyase activity
single-strand selective uracil DNA N-glycosylase activity
DNA N-glycosylase activity
DNA-3-methylbase glycosylase activity
metal ion binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding
nicotinamide riboside hydrolase activity
nicotinic acid riboside hydrolase activity
deoxyribonucleoside 5'-monophosphate N-glycosidase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700002637.mm.1	NM_008743.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700002637.mm.1	NM_008743.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700002637.mm.1	TC1700000346.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1700002638.mm.1	NM_008743.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700002638.mm.1	NM_008743.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700002638.mm.1	TC1700000346.mm.1	MTA TC