Mm00488369_s1

• Gene Symbol: Sox2
• Gene Name: SRY (sex determining region Y)-box 2
• Gene Aliases: Sox-2, lcc, ysb
• Chromosome Location: Chr.3: 34650005 - 34652461 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Sox2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011443.3	NP_035573.3	1	960		68
GenBank mRNA	AB108673.1	-	1	582		68
	AB221649.1	-	1	549		68
	AK131933.1	-	1	398		68
	AK149358.1	-	1	283		68
	BC057574.1	-	1	831	6413283	68
	U31967.1	-	1	910		68

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0300000244.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Mouse Stem Cell Pluripotency, Inventoried, Mouse_Stem_Cell, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Sox2

Panther Classification:

Molecular Function -

HMG box transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
osteoblast differentiation
cell fate specification
endodermal cell fate specification
positive regulation of neuroblast proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cell cycle arrest
multicellular organism development
sensory perception of sound
response to organic substance
regulation of gene expression
stem cell population maintenance
forebrain neuron differentiation
adenohypophysis development
cerebral cortex development
positive regulation of cell-cell adhesion
negative regulation of Wnt signaling pathway
male genitalia development
positive regulation of epithelial cell differentiation
olfactory placode formation
response to retinoic acid
somatic stem cell population maintenance
inner ear morphogenesis
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MAPK cascade
tongue development
cell fate commitment
negative regulation of cell differentiation
positive regulation of cell differentiation
negative regulation of neuron differentiation
positive regulation of neuron differentiation
negative regulation of osteoblast differentiation
positive regulation of Notch signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
pigment biosynthetic process
lung alveolus development
embryonic organ development
anatomical structure formation involved in morphogenesis
neuron fate commitment
diencephalon morphogenesis
stem cell differentiation
negative regulation of epithelial cell proliferation
regulation of neurogenesis
detection of mechanical stimulus involved in sensory perception of sound
detection of mechanical stimulus involved in equilibrioception
retina morphogenesis in camera-type eye
lens induction in camera-type eye
epithelial tube branching involved in lung morphogenesis
response to growth factor
negative regulation of canonical Wnt signaling pathway
neuronal stem cell population maintenance

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
chromatin DNA binding
miRNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0300001583.mm.1	NM_011443.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0300001583.mm.1	TC0300000244.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300001585.mm.1	NM_011443.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0300001585.mm.1	TC0300000244.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300001584.mm.1	NM_011443.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0300001584.mm.1	TC0300000244.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300001586.mm.1	NM_011443.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0300001586.mm.1	TC0300000244.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300001587.mm.1	NM_011443.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0300001587.mm.1	TC0300000244.mm.1	MTA TC