Mm00491527_g1

• Gene Symbol: Map3k11
• Gene Name: mitogen-activated protein kinase kinase kinase 11
• Gene Aliases: 2610017K16Rik, Mlk3, PTK1, SPRK
• Chromosome Location: Chr.19: 5688740 - 5702865 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Map3k11
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_022012.3	NP_071295.2	8 - 9	2336		62
GenBank mRNA	AK159518.1	-	6 - 7	1356		62
	BC030928.1	-	6 - 7	889		62
	BC047152.1	-	6 - 7	2083	6476975	62
	BC095963.1	-	8 - 9	2336	5400993	62

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1900000079.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Apoptosis, Protein Kinase, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Map3k11

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

activation of MAPK activity
protein phosphorylation
microtubule-based process
JNK cascade
activation of JNKK activity
activation of JUN kinase activity
cell death
cell proliferation
phosphorylation
positive regulation of apoptotic process
positive regulation of JUN kinase activity
positive regulation of neuron apoptotic process
positive regulation of JNK cascade
protein autophosphorylation

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
JUN kinase kinase kinase activity
MAP kinase kinase kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
mitogen-activated protein kinase kinase binding
mitogen-activated protein kinase kinase kinase binding
identical protein binding
protein homodimerization activity
Rac GTPase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1900000954.mm.1	NM_022012.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1900000954.mm.1	NM_022012.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1900000954.mm.1	TC1900000079.mm.1	MTA TC