Mm00501225_m1

• Gene Symbol: Ptpn2
• Gene Name: protein tyrosine phosphatase, non-receptor type 2
• Gene Aliases: AI325124, Ptpt, TC-PTP
• Chromosome Location: Chr.18: 67665501 - 67724748 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Ptpn2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001127177.1	NP_001120649.1	7 - 8	966		145
	NM_008977.3	NP_033003.1	7 - 8	966		145
GenBank mRNA	AK014528.1	-	7 - 8	933		145
	AK076072.1	-	7 - 8	919		145
	AK132013.1	-	7 - 8	929		145
	BC008269.1	-	7 - 8	940	3602983	145
	M80739.1	-	7 - 8	921		145
	M81477.1	-	7 - 8	921		145
	S52655.1	-	7 - 8	916		145

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1800001512.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protein Phosphatase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ptpn2

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

protein dephosphorylation
negative regulation of cell proliferation
insulin receptor signaling pathway
negative regulation of tumor necrosis factor-mediated signaling pathway
negative regulation of lipid storage
dephosphorylation
B cell differentiation
T cell differentiation
erythrocyte differentiation
peptidyl-tyrosine dephosphorylation
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of tyrosine phosphorylation of Stat6 protein
glucose homeostasis
negative regulation of macrophage differentiation
positive regulation of gluconeogenesis
negative regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
negative regulation of T cell receptor signaling pathway
negative regulation of chemotaxis
negative regulation of interferon-gamma-mediated signaling pathway
negative regulation of type I interferon-mediated signaling pathway
negative regulation of protein tyrosine kinase activity
negative regulation of interleukin-6-mediated signaling pathway
negative regulation of ERK1 and ERK2 cascade
regulation of hepatocyte growth factor receptor signaling pathway
negative regulation of interleukin-2-mediated signaling pathway
negative regulation of prolactin signaling pathway
negative regulation of interleukin-4-mediated signaling pathway
negative regulation of macrophage colony-stimulating factor signaling pathway
negative regulation of positive thymic T cell selection
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of PERK-mediated unfolded protein response
negative regulation of platelet-derived growth factor receptor-beta signaling pathway

Function(s)

phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity
integrin binding
protein binding
hydrolase activity
phosphatase activity
protein kinase binding
syntaxin binding
receptor tyrosine kinase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1800011114.mm.1	NM_001127177.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1800011114.mm.1	NM_001127177.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1800011114.mm.1	NM_008977.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1800011114.mm.1	NM_008977.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1800011114.mm.1	TC1800001512.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1800011116.mm.1	NM_001127177.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1800011116.mm.1	NM_001127177.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1800011116.mm.1	NM_008977.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1800011116.mm.1	NM_008977.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1800011116.mm.1	TC1800001512.mm.1	MTA TC