Mm00515106_m1

• Gene Symbol: Hdac2
• Gene Name: histone deacetylase 2
• Gene Aliases: D10Wsu179e, YAF1, Yy1bp, mRPD3
• Chromosome Location: Chr.10: 36974544 - 37001889 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Hdac2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008229.2	NP_032255.2	2 - 3	373		90
GenBank mRNA	AB221663.1	-	2 - 3	165		90
	AK051753.1	-	2 - 3	348		90
	BC138517.1	-	2 - 3	345	8861537	90
	U31758.1	-	2 - 3	333		90

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1000000312.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Hdac2

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
maintenance of chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
protein deacetylation
positive regulation of cell proliferation
epidermal cell differentiation
positive regulation of epithelial to mesenchymal transition
positive regulation of receptor biosynthetic process
negative regulation of neuron projection development
dendrite development
chromatin modification
histone deacetylation
hippocampus development
neuron differentiation
positive regulation of interleukin-1 production
positive regulation of tumor necrosis factor production
circadian regulation of gene expression
odontogenesis of dentin-containing tooth
positive regulation of tyrosine phosphorylation of Stat3 protein
embryonic digit morphogenesis
ATP-dependent chromatin remodeling
negative regulation of apoptotic process
negative regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of proteolysis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
positive regulation of oligodendrocyte differentiation
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of protein kinase B signaling
cardiac muscle cell development
negative regulation of cardiac muscle cell proliferation
regulation of sarcomere organization
hair follicle placode formation
negative regulation of dendritic spine development
eyelid development in camera-type eye
fungiform papilla formation
cellular response to hydrogen peroxide
histone H3 deacetylation
histone H4 deacetylation
negative regulation of canonical Wnt signaling pathway
regulation of protein deacetylation
negative regulation of peptidyl-lysine acetylation
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
core promoter binding
RNA polymerase II repressing transcription factor binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
histone deacetylase activity
protein binding
transcription factor binding
hydrolase activity
deacetylase activity
enzyme binding
heat shock protein binding
histone deacetylase activity (H3-K14 specific)
chromatin DNA binding
nucleosomal DNA binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
histone deacetylase activity (H3-K9 specific)
protein deacetylase activity
histone deacetylase activity (H4-K16 specific)
Krueppel-associated box domain binding
sequence-specific DNA binding
poly(A) RNA binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
NF-kappaB binding
NAD-dependent histone deacetylase activity (H3-K18 specific)

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1000002048.mm.1	NM_008229.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1000002048.mm.1	NM_008229.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1000002048.mm.1	TC1000000312.mm.1	MTA TC