Mm00518542_m1

• Gene Symbol: Irak3
• Gene Name: interleukin-1 receptor-associated kinase 3
• Gene Aliases: 4833428C18Rik, AI563835, IRAK-M
• Chromosome Location: Chr.10: 120141648 - 120201597 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Irak3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_028679.3	NP_082955.2	2 - 3	396		68
GenBank mRNA	AF461763.1	-	2 - 3	376		68
	AJ440757.2	-	2 - 3	318		68
	AK014783.1	-	2 - 3	447		68
	AK028436.1	-		309		68
	AK029057.1	-	2 - 3	397		68
	AK049210.1	-	2 - 3	427		68
	BC120829.1	-	2 - 3	357	40129752	68
	BC120831.1	-	2 - 3	357	40129754	68
	BC144835.1	-	2 - 3	357		68

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1000003019.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Irak3

Gene Ontology Categories:

Process(es)

negative regulation of cytokine-mediated signaling pathway
toll-like receptor signaling pathway
protein phosphorylation
apoptotic process
signal transduction
response to virus
positive regulation of macrophage tolerance induction
negative regulation of macrophage cytokine production
phosphorylation
cytokine-mediated signaling pathway
negative regulation of NF-kappaB transcription factor activity
response to peptidoglycan
response to lipopolysaccharide
negative regulation of interleukin-12 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
negative regulation of toll-like receptor signaling pathway
intracellular signal transduction
negative regulation of protein catabolic process
regulation of apoptotic process
negative regulation of protein complex disassembly
regulation of protein complex disassembly
response to exogenous dsRNA
negative regulation of MAP kinase activity
negative regulation of innate immune response
protein autophosphorylation
positive regulation of NF-kappaB transcription factor activity
interleukin-1-mediated signaling pathway
response to interleukin-1

Function(s)

nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein homodimerization activity
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1000022571.mm.1	NM_028679.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1000022571.mm.1	NM_028679.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1000022571.mm.1	TC1000003019.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1000022572.mm.1	NM_028679.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1000022572.mm.1	NM_028679.3	Refseq
Affymetrix Mouse Clariom S Array	PSR1000022572.mm.1	TC1000003019.mm.1	MTA TC