Mm00545837_m1

• Gene Symbol: Alox12
• Gene Name: arachidonate 12-lipoxygenase
• Gene Aliases: 9930022G08Rik, Alox12p, P-12LO
• Chromosome Location: Chr.11: 70241455 - 70255386 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Alox12
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_007440.4	NP_031466.2	11 - 12	1606		73
GenBank mRNA	AK036898.1	-	11 - 12	1604		73
	AK036960.1	-	11 - 12	1562		73
	AK087724.1	-	11 - 12	1607		73
	AK172216.1	-	11 - 12	1604		73
	AK172488.1	-	11 - 12	1607		73
	BC152329.1	-	11 - 12	1611	40141477	73
	BC152403.1	-	11 - 12	1611	40141482	73
	S80446.1	-	11 - 12	1618		73
	U04334.1	-	11 - 12	1537		73

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100003090.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Alox12

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

lipid metabolic process
fatty acid metabolic process
movement of cell or subcellular component
positive regulation of cell proliferation
positive regulation of endothelial cell migration
positive regulation of gene expression
negative regulation of muscle cell apoptotic process
positive regulation of cell death
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
positive regulation of cell growth
positive regulation of cell migration
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of endothelial cell differentiation
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of vasodilation
positive regulation of smooth muscle cell proliferation
hepoxilin biosynthetic process
positive regulation of mitochondrial depolarization
oxidation-reduction process
establishment of skin barrier
negative regulation of platelet aggregation
lipoxin A4 biosynthetic process
lipoxin B4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
juvenile hormone epoxide hydrolase activity
linoleate 13S-lipoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
hydrolase activity
epoxide hydrolase B activity
phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity
epoxide hydrolase A activity
phenanthrene-3,4-epoxide hydrolase activity
phenanthrene-1,2-epoxide hydrolase activity
phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity
phenanthrene-epoxide hydrolase activity
phenanthrene-9,10-epoxide hydrolase activity
pyrene-4,5-epoxide hydrolase activity
metal ion binding
dioxygenase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100028514.mm.1	NM_007440.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1100028514.mm.1	TC1100003090.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100028515.mm.1	NM_007440.5	Refseq
Affymetrix Mouse Clariom S Array	PSR1100028515.mm.1	TC1100003090.mm.1	MTA TC