Mm00550338_m1 Best Coverage

• Gene Symbol: Srebf1
• Gene Name: sterol regulatory element binding transcription factor 1
• Gene Aliases: ADD-1, ADD1, D630008H06, SREBP-1, SREBP-1a, SREBP-1c, SREBP1, SREBP1c, bHLHd1
• Chromosome Location: Chr.11: 60199089 - 60222686 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Srebf1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011480.3	NP_035610.1	1 - 2	158		62
GenBank mRNA	AK052628.1	-	1 - 2	159		62
	AK150052.1	-	1 - 2	147		62
	AK154424.1	-	1 - 2	141		62
	AK169607.1	-	1 - 2	159		62
	BC056922.1	-	1 - 2	140	6824948	62

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100002869.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Recommended Assay, Mus musculus, Mouse Estrogen Panel, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Srebf1

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of heart rate by chemical signal
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
insulin receptor signaling pathway
lipid biosynthetic process
cellular response to starvation
response to glucose
positive regulation of triglyceride biosynthetic process
regulation of fatty acid metabolic process
positive regulation of histone deacetylation
regulation of protein stability
positive regulation of cholesterol biosynthetic process
positive regulation of fatty acid biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of insulin secretion
regulation of insulin secretion
regulation of mitophagy
regulation of protein targeting to mitochondrion

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein kinase binding
protein complex binding
sterol response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100026098.mm.1	NM_011480.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1100026098.mm.1	TC1100002869.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100026094.mm.1	NM_011480.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1100026094.mm.1	TC1100002869.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100026095.mm.1	NM_011480.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1100026095.mm.1	TC1100002869.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100026093.mm.1	NM_011480.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1100026093.mm.1	TC1100002869.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	909582	-	-