Mm00550825_m1

• Gene Symbol: Pink1
• Gene Name: PTEN induced putative kinase 1
• Gene Aliases: 1190006F07Rik, AU042772, AW557854, BRPK, mFLJ00387
• Chromosome Location: Chr.4: 138313409 - 138326296 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pink1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_026880.2	NP_081156.2	5 - 6	1196		79
GenBank mRNA	AB053476.1	-	5 - 6	1128		79
	AF316872.1	-	5 - 6	1174		79
	AK050322.1	-	5 - 6	1176		79
	AK155474.1	-	5 - 6	1182		79
	AK165480.1	-	5 - 6	1175		79
	AK220318.1	-	5 - 6	1150		79
	BC018561.1	-	5 - 6	1020		79
	BC018594.1	-	5 - 6			79
	BC054349.1	-	1 - 2			79
	BC067066.1	-	5 - 6	1164	30542123	79
	BC069968.1	-	6 - 7	1054		79

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0400003821.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pink1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

mitophagy
positive regulation of protein phosphorylation
regulation of oxidative phosphorylation
protein phosphorylation
autophagy
response to stress
response to oxidative stress
mitochondrion organization
regulation of hydrogen peroxide metabolic process
negative regulation of gene expression
regulation of mitochondrion organization
positive regulation of macroautophagy
negative regulation of macroautophagy
phosphorylation
protein ubiquitination
peptidyl-serine phosphorylation
respiratory electron transport chain
regulation of protein ubiquitination
positive regulation of synaptic transmission, dopaminergic
positive regulation of peptidyl-serine phosphorylation
positive regulation of dopamine secretion
positive regulation of catecholamine secretion
cellular response to oxidative stress
positive regulation of protein dephosphorylation
intracellular signal transduction
positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of protein complex assembly
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
positive regulation of translation
protein stabilization
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of mitochondrial membrane potential
cellular response to hypoxia
positive regulation of mitochondrial fission
positive regulation of release of cytochrome c from mitochondria
negative regulation of mitochondrial fission
cellular response to toxic substance
mitophagy in response to mitochondrial depolarization
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of autophagosome assembly
positive regulation of mitochondrial electron transport, NADH to ubiquinone
negative regulation of mitophagy
negative regulation of oxidative stress-induced cell death
regulation of protein targeting to mitochondrion
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
positive regulation of cristae formation
positive regulation of protein targeting to mitochondrion
regulation of reactive oxygen species metabolic process
negative regulation of reactive oxygen species metabolic process

Function(s)

nucleotide binding
magnesium ion binding
protease binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
calcium-dependent protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
ubiquitin protein ligase binding
protein kinase B binding
metal ion binding
C3HC4-type RING finger domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0400031484.mm.1	TC0400003821.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0400031484.mm.1	NM_026880.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400031484.mm.1	NM_026880.2	Refseq