Mm00617506_m1

• Gene Symbol: Thra
• Gene Name: thyroid hormone receptor alpha
• Gene Aliases: 6430529J03Rik, AW259572, Erba, Nr1a1, Rvr, T3R[a], T3Ralpha, Thra1, Thra2
• Chromosome Location: Chr.11: 98741873 - 98765111 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Thra
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_178060.3	NP_835161.1	4 - 5	657		72
GenBank mRNA	AK078233.1	-	4 - 5	657		72
	BC046795.1	-		629	5717946	72
	X07750.1	-	3 - 4	227		72
	X07751.1	-		227		72
	X07752.1	-		227		72
	X51983.1	-	3 - 4	231		72

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1100001580.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Nuclear Receptor, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Thra

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

cartilage condensation
ossification
regulation of thyroid hormone mediated signaling pathway
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
learning or memory
regulation of heart contraction
female courtship behavior
response to cold
hormone-mediated signaling pathway
organ morphogenesis
positive regulation of myotube differentiation
negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
erythrocyte differentiation
intracellular receptor signaling pathway
thyroid gland development
regulation of myeloid cell apoptotic process
cytoplasmic sequestering of transcription factor
steroid hormone mediated signaling pathway
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
regulation of lipid catabolic process
Type I pneumocyte differentiation
negative regulation of DNA-templated transcription, initiation

Function(s)

steroid receptor RNA activator RNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
steroid hormone receptor activity
single-stranded RNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
thyroid hormone receptor activity
protein binding
transcription factor binding
zinc ion binding
TBP-class protein binding
protein domain specific binding
chromatin DNA binding
protein complex binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
intronic transcription regulatory region DNA binding
metal ion binding
protein heterodimerization activity
protein dimerization activity
thyroid hormone binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1100014696.mm.1	NM_178060.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1100014696.mm.1	TC1100001580.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1100014694.mm.1	NM_178060.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1100014694.mm.1	TC1100001580.mm.1	MTA TC