Mm00660192_g1

• Gene Symbol: Pitx2
• Gene Name: paired-like homeodomain transcription factor 2
• Gene Aliases: 9430085M16Rik, Brx1, Brx1b, Munc30, Otlx2, Ptx2, Rieg
• Chromosome Location: Chr.3: 129199878 - 129219594 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Pitx2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011098.4	NP_035228.2	2 - 3	338		113
GenBank mRNA	AB006321.1	-	2 - 3	298		113
	U80010.1	-	2 - 3	273		113

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0300001300.mm.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Detect Genomic DNA, Mus musculus, Mouse Wnt Panel, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Pitx2

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
patterning of blood vessels
vasculogenesis
in utero embryonic development
neuron migration
extraocular skeletal muscle development
atrioventricular valve development
cardiac neural crest cell migration involved in outflow tract morphogenesis
pulmonary myocardium development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
determination of left/right symmetry
heart development
skeletal muscle tissue development
myoblast fusion
anatomical structure morphogenesis
organ morphogenesis
Wnt signaling pathway
subthalamic nucleus development
hypothalamus cell migration
pituitary gland development
lung development
regulation of cell migration
embryonic camera-type eye development
embryonic hindlimb morphogenesis
vascular smooth muscle cell differentiation
deltoid tuberosity development
regulation of cell proliferation
odontogenesis
camera-type eye development
positive regulation of DNA binding
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
spleen development
embryonic digestive tract morphogenesis
cardiac muscle tissue development
cardiac muscle cell differentiation
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle cell development
digestive system development
ventricular septum morphogenesis
left lung morphogenesis
pulmonary vein morphogenesis
superior vena cava morphogenesis
endodermal digestive tract morphogenesis
iris morphogenesis
cell proliferation involved in outflow tract morphogenesis
left/right axis specification
positive regulation of myoblast proliferation

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
RNA polymerase II transcription coactivator activity
transcriptional repressor activity, RNA polymerase II transcription factor binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
chromatin DNA binding
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
phosphoprotein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0300010527.mm.1	NM_011098.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0300010527.mm.1	TC0300001300.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0300010528.mm.1	NM_001286942.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0300010528.mm.1	NM_011098.4	Refseq
Affymetrix Mouse Clariom S Array	PSR0300010528.mm.1	TC0300001300.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	327074	-	-