Mm00802892_g1

• Gene Symbol: Lck
• Gene Name: lymphocyte protein tyrosine kinase
• Gene Aliases: Hck-3, Lsk, Lskt, p56<lck>, p56Lck
• Chromosome Location: Chr.4: 129548344 - 129573641 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Lck
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001162432.1	NP_001155904.1	4 - 5	370		100
	NM_001162433.1	NP_001155905.1	4 - 5	412		100
	NM_010693.3	NP_034823.1	3 - 4	467		100
GenBank mRNA	AK088001.1	-	3 - 4	468		100
	AK134013.1	-	3 - 4	457		100
	BC011474.1	-	4 - 5	377	4191610	100
	BQ563042.1	-	4 - 5	361		100
	CA577097.1	-	1 - 2	103		100
	M12056.1	-	3 - 4	443		100
	X03533.1	-	3 - 4	473		100

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Kinase, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Lck

Gene Ontology Categories:

Process(es)

protein phosphorylation
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
response to mechanical stimulus
response to metal ion
positive regulation of gene expression
phosphorylation
dephosphorylation
peptidyl-tyrosine phosphorylation
T cell differentiation
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
response to drug
positive regulation of tyrosine phosphorylation of Stat5 protein
response to hydrogen peroxide
regulation of apoptotic process
innate immune response
positive regulation of gamma-delta T cell differentiation
protein autophosphorylation
B cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
release of sequestered calcium ion into cytosol
positive regulation of uterine smooth muscle contraction
cellular response to peptide hormone stimulus
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
glycoprotein binding
antigen binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein serine/threonine phosphatase activity
receptor binding
protein binding
ATP binding
protein C-terminus binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
protein phosphatase binding
protein complex binding
SH2 domain binding
CD4 receptor binding
CD8 receptor binding
identical protein binding
phosphatidylinositol 3-kinase binding
ATPase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0400029373.mm.1	TC0400003602.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0400029373.mm.1	NM_001162432.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400029373.mm.1	NM_001162432.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400029373.mm.1	NM_001162433.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400029373.mm.1	NM_001162433.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400029373.mm.1	NM_010693.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400029373.mm.1	NM_010693.3	Refseq