Mm00803708_m1

• Gene Symbol: Map3k1
• Gene Name: mitogen-activated protein kinase kinase kinase 1
• Gene Aliases: MAPKKK1, MEKK1, Mekk
• Chromosome Location: Chr.13: 111746433 - 111818269 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Map3k1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_011945.2	NP_036075.2	17 - 18	4077		91
GenBank mRNA	AF117340.1	-	17 - 18	4077		91
	L13103.1	-	7 - 8	2086		91
	U23470.1	-	4 - 5	1678		91

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1300002667.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Kinase, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Map3k1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
epithelial cell morphogenesis
protein phosphorylation
transforming growth factor beta receptor signaling pathway
JNK cascade
activation of JNKK activity
activation of JUN kinase activity
regulation of mitotic cell cycle
apoptotic mitochondrial changes
phosphorylation
protein ubiquitination
regulation of cell migration
positive regulation of actin filament polymerization
wound healing
regulation of apoptotic process
camera-type eye development
eyelid development in camera-type eye

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
JUN kinase kinase kinase activity
MAP kinase kinase kinase activity
ubiquitin-protein transferase activity
protein binding
ATP binding
zinc ion binding
JUN kinase binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding
mitogen-activated protein kinase kinase binding
sphingolipid binding
metal ion binding
mitogen-activated protein kinase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1300018058.mm.1	NM_011945.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1300018058.mm.1	NM_011945.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1300018058.mm.1	TC1300002667.mm.1	MTA TC