Mm01202306_m1

• Gene Symbol: Eif2ak1
• Gene Name: eukaryotic translation initiation factor 2 alpha kinase 1
• Gene Aliases: HCR, Hri
• Chromosome Location: Chr.5: 143871862 - 143902717 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Eif2ak1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_013557.2	NP_038585.2		887		91
GenBank mRNA	AK156492.1	-		846		91
	AK173160.1	-		837		91
	AK215017.1	-	3 - 4	236		91
	AY033898.1	-		872		91
	BC028923.1	-		859	4164417	91
	BC111035.1	-		838	5357121	91

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0500001741.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Eif2ak1

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

acute inflammatory response
regulation of translation
protein phosphorylation
phagocytosis
negative regulation of cell proliferation
regulation of translational initiation by eIF2 alpha phosphorylation
regulation of eIF2 alpha phosphorylation by heme
phosphorylation
negative regulation of translation
macrophage differentiation
protoporphyrinogen IX metabolic process
regulation of hemoglobin biosynthetic process
negative regulation of hemoglobin biosynthetic process
iron ion homeostasis

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
heme binding
protein homodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0500016016.mm.1	TC0500001741.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0500016016.mm.1	NM_013557.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0500016016.mm.1	NM_013557.2	Refseq