Mm01215491_m1

• Gene Symbol: Fgfr1
• Gene Name: fibroblast growth factor receptor 1
• Gene Aliases: AW208770, Eask, FLG, Fgfr-1, Flt-2, Hspy, MFR, bFGF-R-1, c-fgr
• Chromosome Location: Chr.8: 25513623 - 25575718 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Fgfr1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001079908.2	NP_001073377.1	6 - 7	1503		66
	NM_001079909.2	NP_001073378.1	5 - 6	1242		66
	NM_010206.3	NP_034336.2	6 - 7	1509		66
GenBank mRNA	AF176552.1	-	4 - 5	534		66
	AK028354.1	-	5 - 6	682		66
	AK049704.1	-	6 - 7	1469		66
	BC010200.1	-	6 - 7	1402	3967874	66
	BC033447.1	-	4 - 5	505	4037899	66
	M33760.1	-	4 - 5	526		66
	U22324.1	-	5 - 6	807		66
	U23445.1	-	4 - 5	540		66
	X51893.1	-	6 - 7	864		66

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0800000321.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Fgfr1

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
ureteric bud development
in utero embryonic development
organ induction
positive regulation of mesenchymal cell proliferation
chondrocyte differentiation
protein phosphorylation
brain development
salivary gland morphogenesis
sensory perception of sound
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of gene expression
negative regulation of gene expression
positive regulation of phospholipase C activity
positive regulation of neuron projection development
phosphorylation
peptidyl-tyrosine phosphorylation
stem cell population maintenance
orbitofrontal cortex development
motogenic signaling involved in postnatal olfactory bulb interneuron migration
ventricular zone neuroblast division
central nervous system neuron development
lung development
embryonic limb morphogenesis
midbrain development
neuron projection development
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
regulation of cell proliferation
inner ear morphogenesis
outer ear morphogenesis
middle ear morphogenesis
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of neuron differentiation
negative regulation of osteoblast differentiation
positive regulation of cell cycle
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
paraxial mesoderm development
regulation of lateral mesodermal cell fate specification
cell maturation
blood vessel morphogenesis
generation of neurons
mesenchymal cell differentiation
regulation of sensory perception of pain
positive regulation of cardiac muscle cell proliferation
auditory receptor cell development
branching involved in salivary gland morphogenesis
lung-associated mesenchyme development
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
vasculogenesis involved in coronary vascular morphogenesis
regulation of stem cell proliferation
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

nucleotide binding
glycoprotein binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
protein binding
ATP binding
heparin binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
fibroblast growth factor binding
protein complex binding
identical protein binding
protein homodimerization activity
cell adhesion molecule binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0800002374.mm.1	NM_001079908.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0800002374.mm.1	NM_001079909.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0800002374.mm.1	NM_010206.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0800002374.mm.1	TC0800000321.mm.1	MTA TC