Mm01216865_m1

• Gene Symbol: Topors
• Gene Name: topoisomerase I binding, arginine/serine-rich
• Gene Aliases: AW105885, LUN, TP53BPL, p53BP3/LUN
• Chromosome Location: Chr.4: 40259606 - 40269841 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Topors
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_134097.3	NP_598858.2	1 - 2	171		75
GenBank mRNA	AB072395.1	-	1 - 2	128		75
	AB104865.1	-	1 - 2	156		75
	AK044564.1	-	1 - 2	149		75
	AK134075.1	-	1 - 2	167		75
	AK140250.1	-	1 - 2	172		75
	AK143025.1	-	1 - 2	152		75
	AK153743.1	-	1 - 2	158		75
	BC019421.1	-	1 - 2	129		75
	BC037141.1	-	1 - 2	149		75
	BC040797.1	-	1 - 2	159	3492178	75

More Information

Additional Information:

This assay is in the 5'UTR region of the AB072395.1, AB104865.1, AK044564.1, AK134075.1, AK140250.1, AK143025.1, AK153743.1, BC019421.1, BC037141.1, BC040797.1, NM_134097.3 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Topors

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

ubiquitin-dependent protein catabolic process
protein monoubiquitination
cellular response to DNA damage stimulus
intrinsic apoptotic signaling pathway in response to DNA damage
protein sumoylation
protein localization to nucleus
regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of transcription, DNA-templated
positive regulation of ubiquitin-protein transferase activity
maintenance of protein location in nucleus
protein K48-linked ubiquitination

Function(s)

DNA binding
antigen binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
SUMO transferase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
DNA topoisomerase binding
metal ion binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0400019646.mm.1	NM_134097.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400019646.mm.1	NM_134097.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0400019646.mm.1	TC0400002436.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR0400019647.mm.1	NM_134097.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0400019647.mm.1	NM_134097.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0400019647.mm.1	TC0400002436.mm.1	MTA TC