Mm01218488_m1

• Gene Symbol: Fgfr1
• Gene Name: fibroblast growth factor receptor 1
• Gene Aliases: AW208770, Eask, FLG, Fgfr-1, Flt-2, Hspy, MFR, bFGF-R-1, c-fgr
• Chromosome Location: Chr.8: 25513623 - 25575718 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Fgfr1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001079908.2	NP_001073377.1	7 - 8	1695		65
	NM_001079909.2	NP_001073378.1	6 - 7	1434		65
	NM_010206.3	NP_034336.2	7 - 8	1701		65
GenBank mRNA	AK028354.1	-	6 - 7	874		65
	AK049704.1	-	7 - 8	1661		65
	BC010200.1	-	7 - 8	1594	3967874	65
	BC033447.1	-	5 - 6	697	4037899	65
	M28998.1	-	6 - 7	999		65
	M33760.1	-	5 - 6	718		65
	M65053.1	-	6 - 7	972		65
	U22324.1	-	6 - 7	999		65
	U23445.1	-	5 - 6	732		65
	X51893.1	-	7 - 8	1056		65
	X57790.1	-	6 - 7	936		65

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0800000321.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Fgfr1

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
ureteric bud development
in utero embryonic development
organ induction
positive regulation of mesenchymal cell proliferation
chondrocyte differentiation
protein phosphorylation
brain development
salivary gland morphogenesis
sensory perception of sound
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of gene expression
negative regulation of gene expression
positive regulation of phospholipase C activity
positive regulation of neuron projection development
phosphorylation
peptidyl-tyrosine phosphorylation
stem cell population maintenance
orbitofrontal cortex development
motogenic signaling involved in postnatal olfactory bulb interneuron migration
ventricular zone neuroblast division
central nervous system neuron development
lung development
embryonic limb morphogenesis
midbrain development
neuron projection development
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
regulation of cell proliferation
inner ear morphogenesis
outer ear morphogenesis
middle ear morphogenesis
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of neuron differentiation
negative regulation of osteoblast differentiation
positive regulation of cell cycle
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
paraxial mesoderm development
regulation of lateral mesodermal cell fate specification
cell maturation
blood vessel morphogenesis
generation of neurons
mesenchymal cell differentiation
regulation of sensory perception of pain
positive regulation of cardiac muscle cell proliferation
auditory receptor cell development
branching involved in salivary gland morphogenesis
lung-associated mesenchyme development
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
vasculogenesis involved in coronary vascular morphogenesis
regulation of stem cell proliferation
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

nucleotide binding
glycoprotein binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
protein binding
ATP binding
heparin binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
fibroblast growth factor binding
protein complex binding
identical protein binding
protein homodimerization activity
cell adhesion molecule binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0800002379.mm.1	NM_001079908.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0800002379.mm.1	NM_001079909.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0800002379.mm.1	NM_010206.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0800002379.mm.1	TC0800000321.mm.1	MTA TC