Mm01227378_m1

• Gene Symbol: Msh6
• Gene Name: mutS homolog 6 (E. coli)
• Gene Aliases: AU044881, AW550279, GTBP, Gtmbp
• Chromosome Location: Chr.17: 87975050 - 87990892 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Msh6
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_010830.2	NP_034960.1	4 - 5	3260		78
GenBank mRNA	AK010643.1	-	1 - 2	421		78
	AK088259.1	-	4 - 5	3249		78
	BC035274.1	-	2 - 3	2658		78
	BC051160.1	-	4 - 5	3205	4953238	78
	BC051634.1	-	4 - 5	3215	6518577	78
	U42190.1	-	4 - 5	3236		78

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1700001315.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Mus musculus, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Msh6

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

meiotic mismatch repair
DNA repair
mismatch repair
cellular response to DNA damage stimulus
reciprocal meiotic recombination
determination of adult lifespan
intrinsic apoptotic signaling pathway in response to DNA damage
response to UV
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
maintenance of DNA repeat elements
isotype switching
negative regulation of DNA recombination
positive regulation of helicase activity
intrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
magnesium ion binding
four-way junction DNA binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
ATP binding
DNA-dependent ATPase activity
ATPase activity
mismatched DNA binding
guanine/thymine mispair binding
single base insertion or deletion binding
single guanine insertion binding
single thymine insertion binding
oxidized purine DNA binding
MutLalpha complex binding
methylated histone binding
ADP binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1700012004.mm.1	NM_010830.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1700012004.mm.1	NM_010830.2	Refseq
Affymetrix Mouse Clariom S Array	PSR1700012004.mm.1	TC1700001315.mm.1	MTA TC