Mm01231067_g1

• Gene Symbol: Adam17
• Gene Name: a disintegrin and metallopeptidase domain 17
• Gene Aliases: CD156b, Tace
• Chromosome Location: Chr.12: 21323509 - 21373632 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Adam17
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001277266.1	NP_001264195.1	14 - 15	1904		83
	NM_001291871.1	NP_001278800.1	13 - 14	1866		83
	NM_009615.6	NP_033745.4	13 - 14	1847		83
	NR_102380.1		10 - 11	1490		83
	NR_120376.1		13 - 14	1847		83
GenBank mRNA	AB021709.1	-	13 - 14	1808		83
	AK137183.1	-	6 - 7	2056		83
	AK137693.1	-	13 - 14	1754		83
	AK139471.1	-	13 - 14	1753		83
	AK142441.1	-	13 - 14	1806		83
	AK144161.1	-	14 - 15	1834		83
	AK149288.1	-	13 - 14	1750		83
	AK211820.1	-	2 - 3	133		83
	BC026052.1	-	10 - 11	1386		83
	BC048792.1	-	13 - 14	1754		83
	BC094655.1	-	13 - 14	1761	5705503	83
	BC114999.1	-	13 - 14	1707	6506501	83
	BC138416.1	-	13 - 14	1726	8861436	83
	BC138420.1	-	13 - 14	1726	8861440	83
	BC145270.1	-	13 - 14	1726	9053824	83
	U69613.1	-	13 - 14	1715		83
	U69614.1	-	13 - 14	1799		83

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1200001490.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protease, Mammalian Gene Collection, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Adam17

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

response to hypoxia
positive regulation of protein phosphorylation
germinal center formation
proteolysis
membrane protein ectodomain proteolysis
cell adhesion
epidermal growth factor receptor signaling pathway
Notch signaling pathway
Notch receptor processing
positive regulation of cell proliferation
positive regulation of T cell chemotaxis
B cell differentiation
positive regulation of cell growth
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
response to lipopolysaccharide
positive regulation of chemokine production
regulation of mast cell apoptotic process
T cell differentiation in thymus
cell adhesion mediated by integrin
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
response to drug
negative regulation of apoptotic process
positive regulation of epidermal growth factor-activated receptor activity
spleen development
cell motility
defense response to Gram-positive bacterium
PMA-inducible membrane protein ectodomain proteolysis
positive regulation of cellular component movement
response to high density lipoprotein particle

Function(s)

metalloendopeptidase activity
Notch binding
interleukin-6 receptor binding
integrin binding
protein binding
peptidase activity
metallopeptidase activity
zinc ion binding
hydrolase activity
SH3 domain binding
PDZ domain binding
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1200010453.mm.1	NM_001277266.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1200010453.mm.1	NM_009615.6	Refseq
Affymetrix Mouse Clariom S Array	PSR1200010453.mm.1	NR_102380.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1200010453.mm.1	TC1200001490.mm.1	MTA TC