Mm01231071_m1

• Gene Symbol: Adam17
• Gene Name: a disintegrin and metallopeptidase domain 17
• Gene Aliases: CD156b, Tace
• Chromosome Location: Chr.12: 21323509 - 21373632 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Adam17
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001277266.1	NP_001264195.1	1 - 2	295		80
	NM_001291871.1	NP_001278800.1	1 - 2	295		80
	NM_009615.6	NP_033745.4	1 - 2	295		80
	NR_120376.1		1 - 2	295		80
GenBank mRNA	AB021709.1	-	1 - 2	256		80
	AJ007365.1	-	1 - 2	95		80
	AK137693.1	-	1 - 2	202		80
	AK139471.1	-	1 - 2	201		80
	AK142441.1	-	1 - 2	235		80
	AK144161.1	-	1 - 2	225		80
	AK149288.1	-	1 - 2	198		80
	AK149614.1	-	1 - 2	202		80
	AK165739.1	-	1 - 2	202		80
	BC048792.1	-	1 - 2	203		80
	BC094655.1	-	1 - 2	209	5705503	80
	BC114999.1	-	1 - 2	155	6506501	80
	BC138416.1	-	1 - 2	174	8861436	80
	BC138420.1	-	1 - 2	174	8861440	80
	BC145270.1	-	1 - 2	174	9053824	80
	CA325381.1	-	1 - 2	263		80
	U69613.1	-	1 - 2	163		80
	U69614.1	-	1 - 2	247		80

More Information

Additional Information:

This assay is in the 5'UTR region of the NM_001291871.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protease, Mammalian Gene Collection, Mus musculus, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Adam17

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

response to hypoxia
positive regulation of protein phosphorylation
germinal center formation
proteolysis
membrane protein ectodomain proteolysis
cell adhesion
epidermal growth factor receptor signaling pathway
Notch signaling pathway
Notch receptor processing
positive regulation of cell proliferation
positive regulation of T cell chemotaxis
B cell differentiation
positive regulation of cell growth
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
response to lipopolysaccharide
positive regulation of chemokine production
regulation of mast cell apoptotic process
T cell differentiation in thymus
cell adhesion mediated by integrin
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
response to drug
negative regulation of apoptotic process
positive regulation of epidermal growth factor-activated receptor activity
spleen development
cell motility
defense response to Gram-positive bacterium
PMA-inducible membrane protein ectodomain proteolysis
positive regulation of cellular component movement
response to high density lipoprotein particle

Function(s)

metalloendopeptidase activity
Notch binding
interleukin-6 receptor binding
integrin binding
protein binding
peptidase activity
metallopeptidase activity
zinc ion binding
hydrolase activity
SH3 domain binding
PDZ domain binding
metal ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1200010473.mm.1	NM_001277266.1	Refseq
Affymetrix Mouse Clariom S Array	PSR1200010473.mm.1	NM_009615.6	Refseq
Affymetrix Mouse Clariom S Array	PSR1200010473.mm.1	TC1200001490.mm.1	MTA TC

Array Name	Probe IDs	Targets	Target Type
ABI Mouse Genome Survey Microarray	397392	-	-