Mm01245090_g1

• Gene Symbol: Top1
• Gene Name: topoisomerase (DNA) I
• Gene Aliases: AI467334, D130064I21Rik, Top-1
• Chromosome Location: Chr.2: 160645897 - 160722764 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Top1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_009408.2	NP_033434.2	12 - 13	1495		91
GenBank mRNA	CO425650.1	-	2 - 3	300		91
	D10061.1	-	12 - 13	1162		91

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0200002452.mm.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Detect Genomic DNA, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Top1

Panther Classification:

Molecular Function -

DNA topoisomerase

Gene Ontology Categories:

Process(es)

DNA replication
DNA topological change
chromatin remodeling
chromosome segregation
rRNA transcription
circadian regulation of gene expression
embryonic cleavage
rhythmic process

Function(s)

core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase activity
DNA topoisomerase type I activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
isomerase activity
chromatin DNA binding
protein complex binding
poly(A) RNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0200019951.mm.1	NM_009408.2.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200019951.mm.1	NM_009408.2	Refseq
Affymetrix Mouse Clariom S Array	PSR0200019951.mm.1	TC0200002452.mm.1	MTA TC